(Q45873826)

17 December 2017

title

Insertional oncogenesis in gene therapy: how much of a risk? (English)

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17 December 2017

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Sadelain M

1

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17 December 2017

publication date

1 April 2004

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

11

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17 December 2017

issue

7

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17 December 2017

page(s)

569-573

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302243

exact match

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cites work

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

The future for gene therapy--a reevaluation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Gene therapy. Second child in French trial is found to have leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Gene therapy's new era: a balance of unequivocal benefit and unequivocal harm

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Gene therapy insertional mutagenesis insights

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Cytokines and immunodeficiency diseases

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Gamma chain required for naïve CD4+ T cell survival but not for antigen proliferation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

IL-15 and IL-2: a matter of life and death for T cells in vivo

21 January 2018

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Occurrence of leukaemia following gene therapy of X-linked SCID.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

Chromatin insulators and boundaries: effects on transcription and nuclear organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

The cHS4 insulator increases the probability of retroviral expression at random chromosomal integration sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

New genes involved in cancer identified by retroviral tagging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

inferred from DOI database lookup

7 January 2021

based on heuristic

Costimulation of transduced T lymphocytes via T cell receptor-CD3 complex and CD28 leads to increased transcription of integrated retrovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

inferred from DOI database lookup

7 January 2021

based on heuristic

Safety of retroviral gene marking with a truncated NGF receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302243

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.GT.3302243

1 reference

17 December 2017

Dimensions Publication ID

1047354190

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1 reference

17 December 2017