(Q45877347)

English

Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts

scientific article published in July 1996

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scholarly article

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/8699255

Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts (English)

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/8699255

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

author name string

C Bencsics

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

S R Wachtel

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

S Milstien

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

K Hatakeyama

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

J B Becker

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

1 July 1996

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/8699255

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

16

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

4449-4456

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

14

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

Entrance of tetrahydropterin derivatives in brain after peripheral administration: effect on biogenic amine metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral effects and gene delivery in a rat model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biopterin. III. Purification and characterization of enzymes involved in the cerebral synthesis of 7,8-dihydrobiopterin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce l-dopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-3,4-dihydroxyphenylalanine-induced dopamine release in the striatum of intact and 6-hydroxydopamine-treated rats: differential effects of monoamine oxidase A and B inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of microdialysis for monitoring tyrosine hydroxylase activity in the brain of conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin in Striatum: Localization in Dopamine Nerve Terminals and Role in Catecholamine Synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microdialysis monitoring of 3,4-dihydroxyphenylalanine accumulation after decarboxylase inhibition: a means to estimate in vivo changes in tyrosine hydroxylase activity of the rat locus ceruleus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin turnover in cultured rat sympathetic neurons: developmental profile, pharmacologic sensitivity, and relationship to norepinephrine synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of reduced forms of biopterin in biological tissues and fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biopterin cofactor and monoamine-synthesizing monooxygenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An HSV-1 vector expressing tyrosine hydroxylase causes production and release of L-dopa from cultured rat striatal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-3,4-dihydroxyphenylalanine synthesis by genetically modified Schwann cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stability of endogenous tyrosine hydroxylase protein in PC-12 cells differs from that expressed in mouse fibroblasts by gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A RAPID AND SIMPLE RADIOASSAY FOR TYROSINE HYDROXYLASE ACTIVITY

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated body swing test: a new behavioral parameter for rats with 6-hydroxydopamine-induced hemiparkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor-transduced fibroblasts: production of BDNF and effects of grafting to the adult rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of (6R)- and (6S)-tetrahydrobiopterin on L-3,4-dihydroxyphenylalanine (DOPA) formation in NRK fibroblasts transfected with human tyrosine hydroxylase type 2 cDNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and sequencing of cDNA encoding rat GTP cyclohydrolase I. The first enzyme of the tetrahydrobiopterin biosynthetic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripherally Administered Reduced Pterins Do Enter the Brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved retroviral vectors for gene transfer and expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adrenal medulla grafts in the hemiparkinsonian rat: profile of behavioral recovery predicts restoration of the symmetry between the two striata in measures of pre- and postsynaptic dopamine function

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural-targeted gene therapy for rodent and primate hemiparkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological and neurochemical features of cultured primary skin fibroblasts of Fischer 344 rats following striatal implantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively prese

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin-dependent functional recovery in 6-hydroxydopamine-treated rats by intracerebral grafting of fibroblasts transfected with tyrosine hydroxylase cDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo release of dopa and dopamine from genetically engineered cells grafted to the denervated rat striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single human gene encoding multiple tyrosine hydroxylases with different predicted functional characteristics

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human tyrosine hydroxylase cDNA in invertebrate cells using a baculovirus vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of dopamine production by genetically modified primary fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of adenovirus vectors for intracerebral grafting of transfected nervous cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biopterin cofactor biosynthesis: GTP cyclohydrolase, neopterin and biopterin in tissues and body fluids of mammalian species

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grafting fibroblasts genetically modified to produce L-dopa in a rat model of Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin is required for cytokine-induced nitric oxide production in a murine macrophage cell line (RAW 264).

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of L-3,4-dihydroxyphenylalanine by tyrosine hydroxylase cDNA-transfected C6 cells: application for intracerebral grafting

1 reference

https://pubmed.ncbi.nlm.nih.gov/8699255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.16-14-04449.1996

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6578851&resulttype=core&format=json

15 May 2020

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