(Q45877567)

17 December 2017

title

Engineering of highly immunogenic long-lived DC vaccines by antiapoptotic protein gene transfer to enhance cancer vaccine potency (English)

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17 December 2017

author name string

T Yoshikawa

1

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17 December 2017

T Niwa

2

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17 December 2017

H Mizuguchi

3

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17 December 2017

N Okada

4

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17 December 2017

S Nakagawa

5

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17 December 2017

publication date

15 May 2008

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

15

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17 December 2017

issue

19

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17 December 2017

page(s)

1321-1329

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/gt.2008.85

exact match

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cites work

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bcl-xL is critical for dendritic cell survival in vivo.

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Dendritic-cell trafficking to lymph nodes through lymphatic vessels

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The use of dendritic cells in cancer immunotherapy

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The first 1000 dendritic cell vaccinees.

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CD8+ T Cell-Dependent Elimination of Dendritic Cells In Vivo Limits the Induction of Antitumor Immunity

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Immune tolerance after delivery of dying cells to dendritic cells in situ

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A new lease on life for dendritic cell vaccines?

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Regulation of the lifespan in dendritic cell subsets

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TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo

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Bcl-2 controls dendritic cell longevity in vivo

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A Bcl-2-dependent molecular timer regulates the lifespan and immunogenicity of dendritic cells

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An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

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Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors

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Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors

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Protection against ischemic brain injury by protein therapeutics

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Death receptors: signaling and modulation

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Mitochondria and apoptosis

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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In vivo detection of dendritic cell antigen presentation to CD4(+) T cells.

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An essential role for Akt1 in dendritic cell function and tumor immunotherapy.

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Rapid construction of small interfering RNA-expressing adenoviral vectors on the basis of direct cloning of short hairpin RNA-coding DNAs

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Enhancing dendritic cell vaccine potency by combining a BAK/BAX siRNA-mediated antiapoptotic strategy to prolong dendritic cell life with an intracellular strategy to target antigen to lysosomal compartments.

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'Survival gene' Bcl-xl potentiates DNA-raised antitumor immunity

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Generation of dendritic cell-based vaccines for cancer therapy

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Dendritic cells transduced with gp100 gene by RGD fiber-mutant adenovirus vectors are highly efficacious in generating anti-B16BL6 melanoma immunity in mice.

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7 January 2021

Augmentation of the migratory ability of DC-based vaccine into regional lymph nodes by efficient CCR7 gene transduction

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7 January 2021

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

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7 January 2021

A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob

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7 January 2021

A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors

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7 January 2021

Identifiers

DOI

10.1038/GT.2008.85

1 reference

17 December 2017

Dimensions Publication ID

1020340535

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1 reference

17 December 2017