(Q45878227)

17 December 2017

title

Clinical efforts to modulate angiogenesis in the adult: gene therapy versus conventional approaches (English)

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17 December 2017

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G Liau

1

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17 December 2017

E J. Su

series ordinal

2

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17 December 2017

K D. Dixon

series ordinal

3

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17 December 2017

publication date

1 July 2001

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17 December 2017

published in

Drug Discovery Today

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17 December 2017

volume

6

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17 December 2017

issue

13

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17 December 2017

page(s)

689-697

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17 December 2017

Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

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Gene therapy for therapeutic myocardial angiogenesis: a promising synthesis of two emerging technologies

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Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

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Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

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Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

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Role of vascular endothelial growth factor in the regulation of angiogenesis

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Circulating endothelial precursors: mystery, reality, and promise

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Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization

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Angiogenesis in cancer, vascular, rheumatoid and other disease

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7 January 2021

Angiogenesis in cancer and other diseases

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7 January 2021

Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease

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7 January 2021

Therapeutic angiogenesis with basic fibroblast growth factor: technique and early results

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7 January 2021

Effect of intracoronary recombinant human vascular endothelial growth factor on myocardial perfusion: evidence for a dose-dependent effect

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Basic fibroblast growth factor in patients with intermittent claudication: results of a phase I trial

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7 January 2021

Pharmacokinetics and pharmacodynamics of recombinant FGF-2 in a phase I trial in coronary artery disease

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7 January 2021

Angiogenesis factor from human myocardial infarcts

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7 January 2021

Molecular biologic concepts of coronary anastomoses

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7 January 2021

Preclinical and Clinical Studies with Recombinant Human Basic Fibroblast Growth Factor

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7 January 2021

Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion

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7 January 2021

Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart

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7 January 2021

Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors: role of the immune response

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7 January 2021

Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia

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7 January 2021

Acute host-mediated endothelial injury after adenoviral gene transfer in normal rabbit arteries: impact on transgene expression and endothelial function

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7 January 2021

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

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7 January 2021

US gene therapy in crisis

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7 January 2021

Clinical trials in coronary angiogenesis: issues, problems, consensus: An expert panel summary

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7 January 2021

A tumultuous year for gene therapy

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7 January 2021

The clinical manipulation of angiogenesis: pathology, side-effects, surprises, and opportunities with novel human therapies

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7 January 2021

Hypotensive activity of fibroblast growth factor

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7 January 2021

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

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7 January 2021

VEGF gene delivery to myocardium: deleterious effects of unregulated expression

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7 January 2021

Transmyocardial laser revascularization and angiogenesis: the potential for therapeutic benefit

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7 January 2021

Progress in antiangiogenic gene therapy of cancer

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7 January 2021

Antiangiogenic gene therapy

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7 January 2021

Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth.

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7 January 2021

Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor

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7 January 2021

Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice

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7 January 2021

Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2

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7 January 2021

Systemic delivery of antiangiogenic adenovirus AdmATF induces liver resistance to metastasis and prolongs survival of mice

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7 January 2021

Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases

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7 January 2021

Antiangiogenic gene therapy for cancer via systemic administration of adenoviral vectors expressing secretable endostatin

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7 January 2021

Matrix metalloproteinases: biologic activity and clinical implications

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7 January 2021

VEGF: an update on biological and therapeutic aspects

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7 January 2021

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

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7 January 2021

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

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7 January 2021

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma

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7 January 2021

An essential role for p300/CBP in the cellular response to hypoxia

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7 January 2021

10.1016/S1359-6446(01)01809-8

Identifiers

DOI

1 reference

17 December 2017

1 reference

17 December 2017