(Q45881013)

English

Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression

scientific article published on January 1, 1992

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scholarly article

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/1309283

Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1309283

11 September 2022

immediate-early proteins

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1309283

11 September 2022

viral gene expression regulation

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1309283

11 September 2022

author name string

I. L. Smith

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1309283

11 September 2022

M. A. Hardwicke

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1309283

11 September 2022

R. M. Sandri-Goldin

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1309283

11 September 2022

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publication date

1 January 1992

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/1309283

full work available at URL

https://api.elsevier.com/content/article/PII:004268229290062T?httpAccept=text/xml

1 reference

10.1016/0042-6822(92)90062-T

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30 November 2023

https://api.elsevier.com/content/article/PII:004268229290062T?httpAccept=text/plain

1 reference

10.1016/0042-6822(92)90062-T

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30 November 2023

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/1309283

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17 December 2017

http://europepmc.org/abstract/MED/1309283

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17 December 2017

http://europepmc.org/abstract/MED/1309283

1

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/1309283

Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription

1

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A method for isolation of intact, translationally active ribonucleic acid.

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Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4

3

1 reference

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Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175

4

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The products of herpes simplex virus type 1 (HSV-1) immediate early genes 1, 2 and 3 can activate HSV-1 gene expression in trans

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On the Association of Virus Proteins with the Nuclei of Cells Infected with Herpes Simplex Virus

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Inactivation of the shutoff gene (UL41) of herpes simplex virus types 1 and 2.

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Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant

10

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The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule

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Antigenic variants of herpes simplex virus selected with glycoprotein-specific monoclonal antibodies

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Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

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A mutant herpesvirus protein leads to a block in nuclear localization of other viral proteins

16

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Differentiation, not determination, regulates muscle gene activation: transfection of troponin I genes into multipotential and muscle lineages of 10T1/2 cells

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Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient

18

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The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.

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Complete DNA sequence of the short repeat region in the genome of herpes simplex virus type 1.

20

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The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection

21

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A system for shotgun DNA sequencing

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A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

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Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters

25

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Abnormal properties of an immediate early polypeptide in cells infected with the herpes simplex virus type 1 mutant tsK

26

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Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

27

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Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) protein

31

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Herpes simplex virus type 1 ICP27 is an essential regulatory protein.

32

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Method for induction of mutations in physically defined regions of the herpes simplex virus genome

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Expression of herpes simplex virus beta and gamma genes integrated in mammalian cells and their induction by an alpha gene product.

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The alpha protein ICP0 does not appear to play a major role in the regulation of herpes simplex virus gene expression during infection in tissue culture

35

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The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.

36

1 reference

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Mutations in the activation region of herpes simplex virus regulatory protein ICP27 can be trans dominant

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Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation

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Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose

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Transcriptional and post-transcriptional controls establish the cascade of herpes simplex virus protein synthesis

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A major transcriptional regulatory protein (ICP4) of herpes simplex virus type 1 is associated with purified virions.

44

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10.1016/0042-6822(92)90062-T

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30 November 2023

Identifiers

10.1016/0042-6822(92)90062-T

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/1309283

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/1309283

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