(Q45883040)

English

A direct comparison of two nonviral gene therapy vectors for somatic integration: in vivo evaluation of the bacteriophage integrase phiC31 and the Sleeping Beauty transposase

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

A direct comparison of two nonviral gene therapy vectors for somatic integration: in vivo evaluation of the bacteriophage integrase phiC31 and the Sleeping Beauty transposase (English)

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

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Anja Ehrhardt

1

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

Hui Xu

2

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

Zan Huang

3

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

Jeffrey A Engler

4

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

Mark A Kay

5

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

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1 May 2005

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Europe PubMed Central

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17 December 2017

http://europepmc.org/abstract/MED/15851008

Molecular Therapy

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

11

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

5

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

695-706

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

1 reference

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7 January 2021

A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo

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7 January 2021

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Site-specific genomic integration produces therapeutic Factor IX levels in mice

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7 January 2021

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

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Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

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High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

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7 January 2021

Intravenous administration of an AAV-2 vector for the expression of factor IX in mice and a dog model of hemophilia B.

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Sustained phenotypic correction of hemophilia B dogs with a factor IX null mutation by liver-directed gene therapy

1 reference

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7 January 2021

Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector

1 reference

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7 January 2021

Optimization of cis-acting elements for gene expression from nonviral vectors in vivo

1 reference

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7 January 2021

Inclusion of the hepatic locus control region, an intron, and untranslated region increases and stabilizes hepatic factor IX gene expression in vivo but not in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

AAV serotype 2 vectors preferentially integrate into active genes in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

HIV-1 integration in the human genome favors active genes and local hotspots

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Stable nonviral genetic correction of inherited human skin disease

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Phage integrases: biology and applications

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

A phage integrase directs efficient site-specific integration in human cells

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

PhiC31 integrase-mediated nonviral genetic correction of junctional epidermolysis bullosa

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Helper-Independent Sleeping Beauty transposon-transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Episomal persistence of recombinant adenoviral vector genomes during the cell cycle in vivo

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Method for multiple portal vein infusions in mice: quantitation of adenovirus-mediated hepatic gene transfer.

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Long-term and therapeutic-level hepatic gene expression of human factor IX after naked plasmid transfer in vivo

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.01.010

7 January 2021

Chromosomal effects of adeno-associated virus vector integration

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7 January 2021

CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo

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Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

1 reference

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Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells

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7 January 2021

Adeno-associated virus vector integration junctions.

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7 January 2021

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10.1016/J.YMTHE.2005.01.010

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/15851008

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