(Q45884677)

17 December 2017

title

QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis (English)

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17 December 2017

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J-U Appelt

1

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17 December 2017

F A Giordano

2

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17 December 2017

M Ecker

3

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17 December 2017

I Roeder

4

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17 December 2017

N Grund

5

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17 December 2017

A Hotz-Wagenblatt

6

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17 December 2017

G Opelz

7

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17 December 2017

W J Zeller

8

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17 December 2017

H Allgayer

9

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17 December 2017

S Fruehauf

10

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17 December 2017

S Laufs

11

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17 December 2017

publication date

23 April 2009

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

16

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17 December 2017

issue

7

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17 December 2017

page(s)

885-893

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/gt.2009.37

exact match

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Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

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Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

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Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

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7 January 2021

The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery

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7 January 2021

Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Murine leukemia virus vector integration favors promoter regions and regional hot spots in a human T-cell line

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Murine leukemia induced by retroviral gene marking

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

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7 January 2021

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

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7 January 2021

Novel use of polymerase chain reaction to amplify cellular DNA adjacent to an integrated provirus

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Retroviral integration site analysis in hematopoietic stem cells

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

New bioinformatic strategies to rapidly characterize retroviral integration sites of gene therapy vectors.

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Automated analysis of viral integration sites in gene therapy research using the SeqMap web resource

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Genome-wide analyses of avian sarcoma virus integration sites

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7 January 2021

Mouse mammary tumor virus integration site selection in human and mouse genomes

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Human T-cell leukemia virus type 1 integration target sites in the human genome: comparison with those of other retroviruses

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7 January 2021

Genome-wide mapping of foamy virus vector integrations into a human cell line

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7 January 2021

Foamy virus vector integration sites in normal human cells

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

The integration profile of EIAV-based vectors

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7 January 2021

HIV-1 integration in the human genome favors active genes and local hotspots

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7 January 2021

Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.

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7 January 2021

HIV integration site selection: targeting in macrophages and the effects of different routes of viral entry.

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7 January 2021

Lentiviral vector integration sites in human NOD/SCID repopulating cells.

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Integration site choice of a feline immunodeficiency virus vector

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Retroviral DNA integration: viral and cellular determinants of target-site selection

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Hot spots of retroviral integration in human CD34+ hematopoietic cells

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Simian immunodeficiency virus integration preference is similar to that of human immunodeficiency virus type 1.

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Viral determinants of integration site preferences of simian immunodeficiency virus-based vectors

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

HIV integration site selection: analysis by massively parallel pyrosequencing reveals association with epigenetic modifications

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

DNA bar coding and pyrosequencing to analyze adverse events in therapeutic gene transfer

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

cisRED: a database system for genome-scale computational discovery of regulatory elements

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Human MicroRNA targets

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

A census of human cancer genes

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Initial sequencing and analysis of the human genome

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

The Sequence of the Human Genome

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Genome-wide analysis of retroviral DNA integration

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Transcription start regions in the human genome are favored targets for MLV integration

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

BLAT—The BLAST-Like Alignment Tool

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

THE USE OF CONFIDENCE OR FIDUCIAL LIMITS ILLUSTRATED IN THE CASE OF THE BINOMIAL

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

RTCGD: retroviral tagged cancer gene database

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https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

A task framework for the web interface W2H.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2009.37

7 January 2021

Identifiers

DOI

10.1038/GT.2009.37

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017