(Q45884692)

17 December 2017

title

Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB. (English)

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17 December 2017

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Zhengmao Ye

1

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17 December 2017

Ingegerd Hellström

2

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17 December 2017

Martha Hayden-Ledbetter

3

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17 December 2017

Amber Dahlin

4

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17 December 2017

Jeffrey A Ledbetter

5

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17 December 2017

Karl Erik Hellström

6

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17 December 2017

language of work or name

English

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publication date

1 April 2002

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17 December 2017

published in

Nature Medicine

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17 December 2017

volume

8

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17 December 2017

page(s)

343-348

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17 December 2017

issue

4

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/nm0402-343

exact match

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cites work

T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes

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https://api.crossref.org/works/10.1038%2FNM0402-343

Immunity to oncogenic proteins

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Tumor antigens recognized by T cells

21 January 2018

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Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

21 January 2018

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Tumor-induced immune dysfunction

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0402-343

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

21 January 2018

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Enhancement of antitumor immunity by CTLA-4 blockade

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0402-343

Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0402-343

Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0402-343

Therapeutic vaccination for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0402-343

Costimulation by CD28 sFv expressed on the tumor cell surface or as a soluble bispecific molecule targeted to the L6 carcinoma antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0402-343

4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0402-343

Surface expression of CD28 single chain Fv for costimulation by tumor cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0402-343

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity

21 January 2018

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Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0402-343

CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo.

21 January 2018

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Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

21 January 2018

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Costimulation by CD48 and B7-1 induces immunity against poorly immunogenic tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0402-343

Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells

21 January 2018

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Rapid and reliable cloning of antibody variable regions and generation of recombinant single chain antibody fragments

21 January 2018

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Recombinant vaccinia virus vaccine against the human melanoma antigen p97 for use in immunotherapy

21 January 2018

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Adoptive T Cell Therapy of Tumors: Mechanisms Operative in the Recognition and Elimination of Tumor Cells

21 January 2018

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7 January 2021

Cancer vaccines: a road map for the next decade

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7 January 2021

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

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https://api.crossref.org/works/10.1038%2FNM0402-343

7 January 2021

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

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https://api.crossref.org/works/10.1038%2FNM0402-343

7 January 2021

Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway

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https://api.crossref.org/works/10.1038%2FNM0402-343

7 January 2021

The role of B7-2 (CD86) in tumour immunity

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https://api.crossref.org/works/10.1038%2FNM0402-343

7 January 2021

Express yourself or die: peptides, MHC molecules, and NK cells

1 reference

https://api.crossref.org/works/10.1038%2FNM0402-343

7 January 2021

Identifiers

DOI

10.1038/NM0402-343

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017