(Q45886786)

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Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

author name string

Tong Y

1

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

Liu-Chen X

2

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

Ercikan-Abali EA

3

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

Capiaux GM

4

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

Zhao SC

5

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

Banerjee D

6

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

Bertino JR

7

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

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publication date

1 May 1998

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

Journal of Biological Chemistry

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17 December 2017

http://europepmc.org/abstract/MED/9565579

273

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Europe PubMed Central

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17 December 2017

http://europepmc.org/abstract/MED/9565579

19

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

11611-11618

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

The catalytic mechanism and structure of thymidylate synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Nucleotide sequence of a functional cDNA for human thymidylate synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Crystallization of human thymidylate synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Folate-based thymidylate synthase inhibitors as anticancer drugs

1 reference

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21 January 2018

Escherichia coli thymidylate synthase: amino acid substitutions by suppression of amber nonsense mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

High-Level Expression of Human Thymidylate Synthase

1 reference

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21 January 2018

Selection of mammalian thymidine auxotrophic cell mutants defective in thymidylate synthase by their reduced sensitivity to methotrexate

1 reference

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21 January 2018

Overcoming inclusion body formation in a high-level expression system.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Isolation and expression of rat thymidylate synthase cDNA: phylogenetic comparison with human and mouse thymidylate synthases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Kinetics and mechanism of interaction of 10-propargyl-5,8-dideazafolate with thymidylate synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

'Cold SSCP': a simple, rapid and non-radioactive method for optimized single-strand conformation polymorphism analyses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei

1 reference

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21 January 2018

Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate

1 reference

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21 January 2018

Cofactor triggers the conformational change in thymidylate synthase: implications for an ordered binding mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Water-mediated substrate/product discrimination: the product complex of thymidylate synthase at 1.83 A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Amino acid substitution analysis of E. coli thymidylate synthase: the study of a highly conserved region at the N-terminus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1

1 reference

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21 January 2018

The Sensitivity of Single-Strand Conformation Polymorphism Analysis for the Detection of Single Base Substitutions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Secondary alpha-hydrogen isotope effects on the interaction of 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate with thymidylate synthetase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Kinetic characteristics of ICI D1694: a quinazoline antifolate which inhibits thymidylate synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Crystal structure of Escherichia coli thymidylate synthase containing bound 5-fluoro-2'-deoxyuridylate and 10-propargyl-5,8-dideazafolate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Enhancement of thymidylate synthase inhibition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.19.11611

21 January 2018

Identifiers

10.1074/JBC.273.19.11611

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/9565579

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