(Q45889598)

17 December 2017

title

PKC-independent modulation of multidrug resistance in cells with mutant (V185) but not wild-type (G185) P-glycoprotein by bryostatin 1. (English)

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17 December 2017

main subject

multiple drug resistance

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Spitaler M

1

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17 December 2017

Utz I

2

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17 December 2017

Hilbe W

3

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17 December 2017

Hofmann J

4

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17 December 2017

Grunicke HH

5

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17 December 2017

language of work or name

English

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publication date

1 October 1998

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17 December 2017

published in

Biochemical Pharmacology

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17 December 2017

volume

56

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17 December 2017

issue

7

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17 December 2017

page(s)

861-869

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17 December 2017

Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cells

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A phase I study of intravenous bryostatin 1 in patients with advanced cancer

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Binding of [3H]bryostatin 4 to protein kinase C

7 January 2021

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Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60.

7 January 2021

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Complexities of the protein kinase C pathway

7 January 2021

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Differential modulation of protein kinase C by bryostatin 1 and phorbol ester

7 January 2021

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The biochemistry of P-glycoprotein-mediated multidrug resistance

7 January 2021

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Biochemistry of multidrug resistance mediated by the multidrug transporter

7 January 2021

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Effects of phosphorylation of P-glycoprotein on multidrug resistance

7 January 2021

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Phorbol esters induce multidrug resistance in human breast cancer cells

7 January 2021

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Level of protein kinase C activity correlates directly with resistance to adriamycin in murine fibrosarcoma cells.

7 January 2021

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Evidence that protein kinase C-alpha activation is a critical event in phorbol ester-induced multiple drug resistance in human colon cancer cells

7 January 2021

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Mechanism of action of dexniguldipine-HCl (B8509-035), a new potent modulator of multidrug resistance

7 January 2021

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Circumvention of P-glycoprotein-mediated multiple drug resistance by phosphorylation modulators is independent of protein kinases

7 January 2021

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Comparison of staurosporine and four analogues: their effects on growth, rhodamine 123 retention and binding to P-glycoprotein in multidrug-resistant MCF-7/Adr cells

7 January 2021

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Protein kinase C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein

7 January 2021

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Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance

7 January 2021

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Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells

7 January 2021

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Isolation and genetic characterization of human KB cell lines resistant to multiple drugs

7 January 2021

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A new vector using the human multidrug resistance gene as a selectable marker enables overexpression of foreign genes in eukaryotic cells

7 January 2021

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New colorimetric cytotoxicity assay for anticancer-drug screening

7 January 2021

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Reversal of multidrug resistance by B859-35, a metabolite of B859-35, niguldipine, verapamil and nitrendipine

7 January 2021

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Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction

7 January 2021

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An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene

7 January 2021

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Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein

7 January 2021

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Gene transfer of drug resistance genes. Implications for cancer therapy

7 January 2021

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Transfer of the MDR1 gene into haematopoietic cells

7 January 2021

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10.1016/S0006-2952(98)00107-5

7 January 2021

Identifiers

DOI

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17 December 2017

1 reference

17 December 2017