(Q45903757)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23423259%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy (English)

1 reference

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24 February 2020

0 references

4

1 reference

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24 February 2020

Dickson W L Wong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23423259%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Sydney C W Tang

9

1 reference

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24 February 2020

author name string

Miao Lin

1

1 reference

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24 February 2020

Wai Han Yiu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23423259%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Rui Xi Li

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23423259%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Loretta Y Y Chan

6

1 reference

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24 February 2020

Joseph C K Leung

7

1 reference

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24 February 2020

Kar Neng Lai

8

1 reference

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24 February 2020

language of work or name

English

0 references

publication date

20 February 2013

1 reference

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24 February 2020

1 reference

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24 February 2020

volume

83

1 reference

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24 February 2020

issue

5

1 reference

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24 February 2020

page(s)

887-900

1 reference

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Role of inflammation in diabetic nephropathy

24 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

The role of inflammatory cytokines in diabetic nephropathy.

1 reference

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7 January 2021

Clinical and histological correlations of decline in renal function in diabetic patients with proteinuria

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury?

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Activation of tubular epithelial cells in diabetic nephropathy and the role of the peroxisome proliferator-activated receptor-gamma agonist

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Tumor necrosis factor-alpha gene expression in diabetic nephropathy: relationship with urinary albumin excretion and effect of angiotensin-converting enzyme inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-alpha and inducible nitric oxide synthase in diabetic rat glom

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Additive renoprotective effects of B2-kinin receptor blocker and PPAR-γ agonist in uninephrectomized db/db mice.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Intercellular adhesion molecule-1 deficiency is protective against nephropathy in type 2 diabetic db/db mice

1 reference

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7 January 2021

Bradykinin and high glucose promote renal tubular inflammation.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Macrophages in mouse type 2 diabetic nephropathy: correlation with diabetic state and progressive renal injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Global and societal implications of the diabetes epidemic

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Mycophenolate mofetil prevents the development of glomerular injury in experimental diabetes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

The effect of ruboxistaurin on nephropathy in type 2 diabetes

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7 January 2021

The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice.

1 reference

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7 January 2021

Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Toll-like receptor 7 stimulation promotes autoimmune diabetes in the NOD mouse

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema

1 reference

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7 January 2021

High glucose induces toll-like receptor expression in human monocytes: mechanism of activation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

TLR4 links innate immunity and fatty acid-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Angiotensin II upregulates toll-like receptor 4 on mesangial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Role of Toll-like receptor 4 in endotoxin-induced acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Toll-like receptor 4 stimulation triggers crescentic glomerulonephritis by multiple mechanisms including a direct effect on renal cells

1 reference

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7 January 2021

Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice.

1 reference

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7 January 2021

The 'Ethereal' nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not tubulointerstitial injury, in diabetic eNOS knockout mice.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

eNOS knockout mice with advanced diabetic nephropathy have less benefit from renin-angiotensin blockade than from aldosterone receptor antagonists

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Endothelial nitric oxide synthase (eNOS) knockout mice have defective mitochondrial beta-oxidation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Critical role for osteopontin in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Toll-like receptor 4: a novel signaling pathway during renal fibrogenesis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Fibrinogen that appears in Bowman's space of proteinuric kidneys in vivo activates podocyte Toll-like receptors 2 and 4 in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

TLR4 links podocytes with the innate immune system to mediate glomerular injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Candesartan attenuates Angiotensin II-induced mesangial cell apoptosis via TLR4/MyD88 pathway

1 reference

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7 January 2021

Differential regulation of Toll-like receptor 4 gene expression in renal cells by angiotensin II: dependency on AP1 and PU.1 transcriptional sites.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Hyperglycemia induces Toll like receptor 4 expression and activity in mouse mesangial cells: relevance to diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Angiotensin converting enzyme inhibitor but not angiotensin receptor blockade or statin ameliorates murine adriamycin nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Glomerulosclerosis and tubulointerstitial fibrosis are attenuated with 17beta-estradiol in the aging Dahl salt sensitive rat.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.2013.11

7 January 2021

Identifiers

DOI

10.1038/KI.2013.11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23423259%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 February 2020

1020641175

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23423259%20AND%20SRC:MED&resulttype=core&format=json