(Q45911906)

17 December 2017

title

Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3-kinase/Akt signaling-dependent. (English)

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17 December 2017

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6

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17 December 2017

author name string

Gary J Litherland

1

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17 December 2017

Craig Dixon

2

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17 December 2017

Rachel L Lakey

3

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17 December 2017

Timothy Robson

4

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17 December 2017

Debra Jones

5

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17 December 2017

Tim E Cawston

7

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17 December 2017

Andrew D Rowan

8

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17 December 2017

language of work or name

English

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publication date

10 March 2008

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17 December 2017

Journal of Biological Chemistry

published in

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17 December 2017

volume

283

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17 December 2017

issue

21

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17 December 2017

page(s)

14221-14229

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17 December 2017

Signalling through Class I PI3Ks in mammalian cells

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Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration

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21 January 2018

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Synergistic induction of matrix metalloproteinase 1 by interleukin-1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism

21 January 2018

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Necessary role of phosphatidylinositol 3-kinase in transforming growth factor beta-mediated activation of Akt in normal and rheumatoid arthritis synovial fibroblasts

21 January 2018

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IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappaB- and PI3-kinase/Akt-dependent pathways

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Human nasal cartilage responds to oncostatin M in combination with interleukin 1 or tumour necrosis factor alpha by the release of collagen fragments via collagenases

21 January 2018

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Retinoic acid and oncostatin M combine to promote cartilage degradation via matrix metalloproteinase-13 expression in bovine but not human chondrocytes

21 January 2018

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Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors

21 January 2018

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PI 3-kinase p110beta: a new target for antithrombotic therapy

21 January 2018

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A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

21 January 2018

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Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis

21 January 2018

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The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M710136200

1 reference

17 December 2017

1 reference

17 December 2017