(Q45928684)

17 December 2017

title

Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice. (English)

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17 December 2017

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Hatem Abo-Ouf

1

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17 December 2017

Alexander W M Hooper

2

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17 December 2017

Elizabeth J White

3

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17 December 2017

Helena J Janse van Rensburg

4

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17 December 2017

Bernardo L Trigatti

5

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17 December 2017

Suleiman A Igdoura

6

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17 December 2017

publication date

31 May 2013

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17 December 2017

published in

Human Molecular Genetics

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17 December 2017

volume

22

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17 December 2017

issue

19

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17 December 2017

page(s)

3960-3975

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17 December 2017

Cell and gene-based therapies for the lysosomal storage diseases

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Deletion of macrophage-inflammatory protein 1 alpha retards neurodegeneration in Sandhoff disease mice

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Apoptotic cell death in mouse models of GM2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases

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21 January 2018

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Increases in tumor necrosis factor-alpha following transient global cerebral ischemia do not contribute to neuron death in mouse hippocampus.

21 January 2018

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Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation

21 January 2018

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Inflammation and Alzheimer's disease

21 January 2018

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Bone marrow transplantation prolongs life span and ameliorates neurologic manifestations in Sandhoff disease mice

21 January 2018

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Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells

21 January 2018

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NSAIDs increase survival in the Sandhoff disease mouse: synergy with N-butyldeoxynojirimycin

21 January 2018

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TNF-alpha induction of GM2 expression on renal cell carcinomas promotes T cell dysfunction

21 January 2018

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Sialidase-mediated depletion of GM2 ganglioside in Tay-Sachs neuroglia cells

21 January 2018

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Targeting Bid to prevent programmed cell death in neurons.

21 January 2018

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JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Pathogenic cascades in lysosomal disease-Why so complex?

21 January 2018

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Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats

21 January 2018

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Protective role of STAT3 in NMDA and glutamate-induced neuronal death: negative regulatory effect of SOCS3

21 January 2018

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Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity

21 January 2018

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Alterations of the microRNA network cause neurodegenerative disease.

21 January 2018

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Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

21 January 2018

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Membrane tumor necrosis factor (TNF) induces p100 processing via TNF receptor-2 (TNFR2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT250

Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT250

Utility of a neurobehavioral screening battery for differentiating the effects of two pyrethroids, permethrin and cypermethrin.

21 January 2018

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A simple rapid method for ganglioside isolation from small amounts of tissue

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT250

21 January 2018

Identifiers

DOI

10.1093/HMG/DDT250

1 reference

17 December 2017

1 reference

17 December 2017