(Q45935125)

18 December 2017

title

Promise and problems in relating cellular senescence in vitro to aging in vivo. (English)

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18 December 2017

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Harry Rubin

1

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18 December 2017

publication date

1 May 2002

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18 December 2017

Archives of Gerontology and Geriatrics

published in

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18 December 2017

volume

34

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18 December 2017

issue

3

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18 December 2017

page(s)

275-286

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18 December 2017

Telomere length predicts replicative capacity of human fibroblasts

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Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

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7 January 2021

Enzyme patterns in cultured kidney cells

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7 January 2021

Residual bodies and "aging" in cultured human glia cells. Effect of entrance into phase 3 and prolonged periods of confluence

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7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

Evidence for cellular aging in long-term confluent cultures: heritable impairment of proliferation, accumulation of age pigments and their loss in neoplastic transformation

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7 January 2021

Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation

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7 January 2021

Telomeres and senescence: ending the debate

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7 January 2021

The rate of telomere sequence loss in human leukocytes varies with age.

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7 January 2021

Telomerase activity, cell proliferation, and cancer

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7 January 2021

The serial cultivation of human diploid cell strains

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7 January 2021

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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7 January 2021

Telomerase, Cell Immortality, and Cancer

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7 January 2021

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

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7 January 2021

Wild-derived inbred mouse strains have short telomeres

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7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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7 January 2021

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7 January 2021

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7 January 2021

Serial passage of embryonic human astrocytes in serum-free, hormone-supplemented medium

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

The life span of the cultured normal cell: Concepts derived from studies of human lymphoblasts

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7 January 2021

Effect of age on lymphocyte proliferation

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7 January 2021

Lack of replicative senescence in normal rodent glia

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7 January 2021

Developmental and tissue-specific regulation of mouse telomerase and telomere length

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7 January 2021

Morphologic changes accompanying senescence of cultured human diploid cells

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7 January 2021

Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo

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7 January 2021

Regulation of human fibroblast growth rate by both noncycling cell fraction transition probability is shown by growth in 5-bromodeoxyuridine followed by Hoechst 33258 flow cytometry

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7 January 2021

Heritable, population-wide damage to cells as the driving force of neoplastic transformation

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7 January 2021

Cellular aging, destabilization, and cancer

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7 January 2021

Cell aging in vivo and in vitro

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7 January 2021

Telomerase and cellular lifespan: ending the debate?

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7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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7 January 2021

The role of selection in progressive neoplastic transformation

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7 January 2021

Variation in the life-span of clones derived from human diploid cell strains

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7 January 2021

Comparison of doubling numbers attained by cultured animal cells with life span of species

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7 January 2021

Mouse embryonic stem cells exhibit indefinite proliferative potential.

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7 January 2021

Extensive telomere repeat arrays in mouse are hypervariable

1 reference

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7 January 2021

A survey of telomerase activity in human cancer

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7 January 2021

Lack of replicative senescence in cultured rat oligodendrocyte precursor cells

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7 January 2021

The molecular genetics of cellular oncogenes

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7 January 2021

Telomerase expression in chickens: constitutive activity in somatic tissues and down-regulation in culture

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7 January 2021

New link in a web of human genes

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7 January 2021

Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4943%2801%2900221-7

7 January 2021

10.1016/S0167-4943(01)00221-7

Identifiers

DOI

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18 December 2017

release_bll5bcymc5ebvlzwpsx2ua2dpm

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/bll5bcymc5ebvlzwpsx2ua2dpm

24 November 2022

mapped directly with Wikidata item

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18 December 2017