(Q45939966)

18 December 2017

http://europepmc.org/abstract/MED/23575437

title

Ketamine pharmacology: an update (pharmacodynamics and molecular aspects, recent findings). (English)

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18 December 2017

http://europepmc.org/abstract/MED/23575437

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json

14 May 2020

author name string

Thierry Villevieille

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json

14 May 2020

publication date

10 April 2013

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18 December 2017

http://europepmc.org/abstract/MED/23575437

published in

CNS Neuroscience & Therapeutics

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json

14 May 2020

volume

19

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json

14 May 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json

14 May 2020

page(s)

370-380

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json

Sernyl (CI-395) in clinical anaesthesia.

14 May 2020

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21 January 2018

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Ketamine increases the amplitude of the 40-Hz auditory steady-state response in humans.

21 January 2018

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Mid-latency auditory evoked potentials during ketamine anaesthesia in humans.

21 January 2018

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Comparison of the effects of ketamine-midazolam with those of fentanyl-midazolam on cortical somatosensory evoked potentials during major spine surgery.

21 January 2018

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BIS monitoring during midazolam and midazolam-ketamine conscious intravenous sedation for oral surgery

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Psychedelic effects of ketamine in healthy volunteers: relationship to steady-state plasma concentrations

21 January 2018

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Additive interactions between propofol and ketamine when used for anesthesia induction in female patients

21 January 2018

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Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine.

21 January 2018

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21 January 2018

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Concentration-effect relationship of intravenous alfentanil and ketamine on peripheral neurosensory thresholds, allodynia and hyperalgesia of neuropathic pain

21 January 2018

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Pharmacokinetics and analgesic effects of i.m. and oral ketamine

21 January 2018

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Central nervous system effects of subdissociative doses of (S)-ketamine are related to plasma and brain concentrations measured with positron emission tomography in healthy volunteers.

21 January 2018

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Cognitive impairment after small-dose ketamine isomers in comparison to equianalgesic racemic ketamine in human volunteers.

21 January 2018

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Effects of ketamine-induced psychopathological symptoms on continuous overt rhyme fluency

21 January 2018

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Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia

21 January 2018

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The schizophrenia ketamine challenge study debate.

21 January 2018

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Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers

21 January 2018

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Serotonin model of schizophrenia: emerging role of glutamate mechanisms

21 January 2018

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Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics.

21 January 2018

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NMDA receptor hypofunction model of schizophrenia

21 January 2018

1 reference

Glutamate and the neural basis of the subjective effects of ketamine: a pharmaco-magnetic resonance imaging study

21 January 2018

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Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression

21 January 2018

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Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder

21 January 2018

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Ketamine for treatment-resistant unipolar depression: current evidence

21 January 2018

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Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to date

21 January 2018

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Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial

21 January 2018

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Small-dose ketamine improves the postoperative state of depressed patients

21 January 2018

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Depression and pain: does ketamine improve the quality of life of patients in chronic pain by targeting their mood?

21 January 2018

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The nature of sites of general anaesthetic action

21 January 2018

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Intravenous anesthetics differentially modulate ligand-gated ion channels

21 January 2018

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Interaction of the chiral forms of ketamine with opioid, phencyclidine, sigma and muscarinic receptors

21 January 2018

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Dexmedetomidine premedication attenuates ketamine-induced cardiostimulatory effects and postanesthetic delirium.

21 January 2018

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Inhibition of neuronal 5-HT uptake by ketamine, but not halothane, involves disruption of substrate recognition by the transporter.

21 January 2018

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Ketamine inhibits serotonin uptake in vivo.

21 January 2018

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Involvement of purinergic neurotransmission in ketamine induced bladder dysfunction

21 January 2018

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Attenuation of ketamine effects by nimodipine pretreatment in recovering ethanol dependent men: psychopharmacologic implications of the interaction of NMDA and L-type calcium channel antagonists

21 January 2018

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Ketamine inhibits sodium currents in identified cardiac parasympathetic neurons in nucleus ambiguus

21 January 2018

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Molecular actions of racemic ketamine on human CNS sodium channels

21 January 2018

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Ketamine blockade of voltage-gated sodium channels: evidence for a shared receptor site with local anesthetics

21 January 2018

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Reduction of allodynia in patients with complex regional pain syndrome: A double-blind placebo-controlled trial of topical ketamine

21 January 2018

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Interaction of intravenous anesthetics with human neuronal potassium currents in relation to clinical concentrations

21 January 2018

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Neuroprotection of S(+) ketamine isomer in global forebrain ischemia

21 January 2018

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Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential

21 January 2018

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Magnesium--essentials for anesthesiologists

21 January 2018

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Magnesium as an adjuvant to postoperative analgesia: a systematic review of randomized trials

21 January 2018

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Modulation of NMDA receptor function by ketamine and magnesium. Part II: interactions with volatile anesthetics

21 January 2018

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The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain

21 January 2018

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Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons

21 January 2018

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Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures.

21 January 2018

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The micromolar zinc-binding domain on the NMDA receptor subunit NR2B.

21 January 2018

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Ifenprodil, a novel NMDA receptor antagonist: site and mechanism of action

21 January 2018

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The Role of N-Methyl-d-Aspartate (NMDA) Receptors in Pain: A Review

21 January 2018

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PSD-95 is a negative regulator of the tyrosine kinase Src in the NMDA receptor complex

21 January 2018

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The fyn art of N-methyl-D-aspartate receptor phosphorylation

21 January 2018

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Nitric oxide and anesthesia.

21 January 2018

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Activation of peripheral NMDA-nitric oxide cascade in formalin test.

21 January 2018

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Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults

21 January 2018

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'Balanced analgesia' in the perioperative period: is there a place for ketamine?

21 January 2018

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Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes

21 January 2018

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Intervention with spinal NMDA, adenosine, and NO systems for pain modulation.

21 January 2018

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Subunit- and site-specific pharmacology of the NMDA receptor channel

21 January 2018

1 reference

Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions.

21 January 2018

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Activation of mu- and delta-opioid receptors causes presynaptic inhibition of glutamatergic excitation in neocortical neurons

21 January 2018

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Intraoperative high dose fentanyl induces postoperative fentanyl tolerance

21 January 2018

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Acute opioid tolerance: intraoperative remifentanil increases postoperative pain and morphine requirement

21 January 2018

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Can epidural fentanyl induce selective spinal hyperalgesia?

21 January 2018

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No clinical evidence of acute opioid tolerance after remifentanil-based anaesthesia

21 January 2018

1 reference

Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a μ opioid

21 January 2018

1 reference

Involvement of the spinal NMDA receptor/PKCγ signaling pathway in the development of bone cancer pain

21 January 2018

1 reference

N-methyl-D-aspartate (NMDA) receptors, mu and kappa opioid tolerance, and perspectives on new analgesic drug development

21 January 2018

1 reference

Ketamine attenuates and reverses morphine tolerance in rodents.

21 January 2018

1 reference

Long-lasting hyperalgesia induced by fentanyl in rats: preventive effect of ketamine

21 January 2018

1 reference

Excitatory amino acids as a final common pathway for neurologic disorders.

21 January 2018

1 reference

Midazolam and ketamine inhibit glutamate release via a cloned human brain glutamate transporter

21 January 2018

1 reference

Ca2+-independent, but voltage- and activity-dependent regulation of the NMDA receptor outward K+ current in mouse cortical neurons

21 January 2018

1 reference

Amantadine: the journey from fighting flu to treating Parkinson disease.

21 January 2018

1 reference

Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

The utility of ketamine for the preoperative management of a patient with Parkinson's disease.

21 January 2018

1 reference

NMDA Antagonist Neurotoxicity: Mechanism and Prevention

21 January 2018

1 reference

Severe toxic damage to the rabbit spinal cord after intrathecal administration of preservative-free S(+)-ketamine

21 January 2018

1 reference

Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity

21 January 2018

1 reference

Long-term effects of ketamine: evidence for a persisting impairment of source memory in recreational users

21 January 2018

1 reference

Frontal white matter abnormalities following chronic ketamine use: a diffusion tensor imaging study

21 January 2018

1 reference

Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys

21 January 2018

1 reference

Use of anesthetic agents in neonates and young children

21 January 2018

1 reference

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

21 January 2018

1 reference

NMDA and opioid receptors: their interactions in antinociception, tolerance and neuroplasticity

21 January 2018

1 reference

12 December 2020

The effects of ketamine on the temporal summation (wind-up) of the R(III) nociceptive flexion reflex and pain in humans

1 reference

12 December 2020

Preemptive hyperalgesia, not analgesia?

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12 December 2020

PKCgamma contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain.

1 reference

12 December 2020

Pharmacokinetics of ketamine in man

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12 December 2020

Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia.

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12 December 2020

Drug-induced apoptotic neurodegeneration in the developing brain.

1 reference

12 December 2020

[Pharmacodynamic effects of S-(+)-ketamine on EEG, evoked potentials and respiration. A study in the awake dog]

1 reference

12 December 2020

Stereoselective high-performance liquid chromatographic determination of the enantiomers of ketamine and norketamine in plasma

1 reference

12 December 2020

Effect of ketamine on bispectral index during propofol--fentanyl anesthesia: a randomized controlled study.

1 reference

12 December 2020

The role of excitatory amino acids and NMDA receptors in traumatic brain injury

1 reference

12 December 2020

Pharmacokinetic and clinical evaluation of ketamine administered by i.v. and epidural routes.

1 reference

12 December 2020

Effects of Ketamine on Nociceptive Cells in the Medial Medullary Reticular Formation of the Cat

1 reference

12 December 2020

Dissociative anesthesia: further pharmacologic studies and first clinical experience with the phencyclidine derivative CI-581.

1 reference

12 December 2020

Comparison of continuous infusion fentanyl or ketamine versus thiopental--determining the mean effective serum concentrations for outpatient surgery.

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12 December 2020

Ketamine--its pharmacology and therapeutic uses.

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12 December 2020

Physostigmine antagonizes ketamine.

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12 December 2020

Anatomy and physiology of glutamate in the CNS.

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12 December 2020

Inhibition by ketamine of muscarinic acetylcholine receptor function.

1 reference

12 December 2020

The effect of N-methyl-D-aspartate antagonist (ketamine) on single and repeated nociceptive stimuli: a placebo-controlled experimental human study

1 reference

12 December 2020

Polyamine deprivation provokes an antalgic effect

1 reference

12 December 2020

Ketamine potentiates analgesic effect of morphine in postoperative epidural pain control.

1 reference

12 December 2020

N-methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death

1 reference

12 December 2020

Ketamine: teaching an old drug new tricks

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12 December 2020

AMPA/Kainate Receptor Antagonists as Novel Analgesic Agents

1 reference

12 December 2020

The effects of ketamine and propofol on neuronal nicotinic acetylcholine receptors and P2x purinoceptors in PC12 cells.

1 reference

12 December 2020

Identifiers

DOI

10.1111/CNS.12099

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493357&resulttype=core&format=json