(Q45945749)

18 December 2017

title

Pharmacogenetic impact of VKORC1 and CYP2C9 allelic variants on warfarin dose requirements in a hispanic population isolate. (English)

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18 December 2017

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Mauricio Arcos-Burgos

7

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18 December 2017

author name string

Lina Palacio

1

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18 December 2017

Diana Falla

2

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18 December 2017

Ignacio Tobon

3

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18 December 2017

Fernando Mejia

4

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18 December 2017

John E Lewis

5

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18 December 2017

Ariel F Martinez

6

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18 December 2017

Mauricio Camargo

8

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18 December 2017

publication date

29 June 2009

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18 December 2017

Clinical and Applied Thrombosis-Hemostasis

published in

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18 December 2017

volume

16

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18 December 2017

issue

1

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18 December 2017

page(s)

83-90

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18 December 2017

Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range

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Application of a pharmacogenetic-based warfarin dosing algorithm derived from British patients to predict dose in Swedish patients

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Effect of ageing upon warfarin dose requirements: a longitudinal study.

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Pharmacogenetics of oral anticoagulants

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Clinical trials that have influenced the treatment of venous thromboembolism: a historical perspective

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VKORC1: molecular target of coumarins

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Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

21 January 2018

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Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose

21 January 2018

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Genotypes of vitamin K epoxide reductase, gamma-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients.

21 January 2018

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Pharmacogenetics of warfarin: current status and future challenges

21 January 2018

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The pharmocogenomics of warfarin: closing in on personalized medicine

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Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms.

21 January 2018

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Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: comparison with other equations

21 January 2018

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A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

21 January 2018

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Identifying the genotype behind the phenotype: a role model found in VKORC1 and its association with warfarin dosing

21 January 2018

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Attention-deficit/hyperactivity disorder (ADHD): feasibility of linkage analysis in a genetic isolate using extended and multigenerational pedigrees

21 January 2018

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21 January 2018

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Attention-deficit/hyperactivity disorder in a population isolate: linkage to loci at 4q13.2, 5q33.3, 11q22, and 17p11.

21 January 2018

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Frequency of CYP2C9 polymorphisms affecting warfarin metabolism in a large anticoagulant clinic cohort.

21 January 2018

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The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

21 January 2018

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The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients

21 January 2018

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Pharmacogenetics and anticoagulant therapy

21 January 2018

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The pharmacogenetics of coumarin therapy.

21 January 2018

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Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin

21 January 2018

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Vitamin K supplementation can improve stability of anticoagulation for patients with unexplained variability in response to warfarin.

21 January 2018

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VKORC1 gene variations are the major contributors of variation in warfarin dose in Japanese patients.

21 January 2018

1 reference

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Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans

21 January 2018

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The genetic basis of resistance to anticoagulants in rodents

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/1076029608330472

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18 December 2017

1 reference

18 December 2017