(Q45951082)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Design, synthesis and brain uptake of LAT1-targeted amino acid prodrugs of dopamine (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Markus M Forsberg

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jarkko Rautio

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Lauri Peura

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Kalle Malmioja

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Jukka Leppänen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Miia Hämäläinen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Mikko Gynther

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Krista Laine

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

publication date

1 October 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

published in

Pharmaceutical Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

2523-2537

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24137801%20AND%20SRC:MED&resulttype=core&format=json

Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

28 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Crossing the blood-brain barrier: are we getting it right?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Moving beyond rules: the development of a central nervous system multiparameter optimization (CNS MPO) approach to enable alignment of druglike properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Prodrugs and endogenous transporters: are they suitable tools for drug targeting into the central nervous system?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Glucose promoiety enables glucose transporter mediated brain uptake of ketoprofen and indomethacin prodrugs in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Brain uptake of ketoprofen-lysine prodrug in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Large neutral amino acid transporter enables brain drug delivery via prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

A bioreversible prodrug approach designed to shift mechanism of brain uptake for amino-acid-containing anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Synthesis, stability, and pharmacological evaluation of nipecotic acid prodrugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Carrier mediated uptake of L-tyrosine and its competitive inhibition by model tyrosine linked compounds in a rabbit corneal cell line (SIRC)--strategy for the design of transporter/receptor targeted prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

L-DOPA transport properties in an immortalised cell line of rat capillary cerebral endothelial cells, RBE 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Drug insight: Continuous dopaminergic stimulation in the treatment of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Role of organic cation transporters in dopamine uptake across olfactory and nasal respiratory tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Synthesis and pharmacology of centrally acting dopamine derivatives and analogs in relation to Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Site-specific, sustained release of drugs to the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Improved delivery through biological membranes. 11. A redox chemical drug-delivery system and its use for brain-specific delivery of phenylethylamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Direct evidence for brain-specific release of dopamine from a redox delivery system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Novel L-Dopa and dopamine prodrugs containing a 2-phenyl-imidazopyridine moiety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Synthesis of glycosyl derivatives as dopamine prodrugs: interaction with glucose carrier GLUT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Design, synthesis and biological evaluation of glutathione peptidomimetics as components of anti-Parkinson prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

In situ brain perfusion technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Galactosylated dopamine enters into the brain, blocks the mesocorticolimbic system and modulates activity and scanning time in Naples high excitability rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Transporter-mediated effects of diclofenamic acid and its ascorbyl pro-drug in the in vivo neurotropic activity of ascorbyl nipecotic acid conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Lipophilicity in PK design: methyl, ethyl, futile

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Synthesis and characterization of 9-[P-(N, N-dipropyl sulfamide)] benzoylamino-1,2,3,4-4H-acridine--a potential prodrug for the CNS delivery of tacrine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Comparison of the uptake of [3H]-gabapentin with the uptake of L-[3H]-leucine into rat brain synaptosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Interaction between L-DOPA and 3-O-methyl-L-DOPA for transport in immortalised rat capillary cerebral endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0966-3

Expression of substrate specificity in facilitated transport systems

21 January 2018

1 reference

12 December 2020

Transport of gabapentin, a gamma-amino acid drug, by system l alpha-amino acid transporters: a comparative study in astrocytes, synaptosomes, and CHO cells

1 reference

12 December 2020

Synthesis and biological studies of glycosyl dopamine derivatives as potential antiparkinsonian agents

1 reference

12 December 2020

9-BBN: An amino acid protecting group for functionalization of amino acid side chains in organic solvents

1 reference

12 December 2020

Glycosyl derivatives of dopamine and L-dopa as anti-Parkinson prodrugs: synthesis, pharmacological activity and in vitro stability studies

1 reference

12 December 2020

Lisdexamfetamine dimesylate

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of levodopa

1 reference

12 December 2020

Facilitated brain uptake of 4-chlorokynurenine and conversion to 7-chlorokynurenic acid.

1 reference

12 December 2020

An in situ brain perfusion technique to study cerebrovascular transport in the rat.

1 reference

12 December 2020

Pharmacokinetics of Levodopa

1 reference

12 December 2020