(Q45969415)

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Beta-amyloid precursor protein (APP) and APP-RNA are rapidly affected by glutamate in cultured neurons: selective increase of mRNAs encoding a Kunitz protease inhibitor domain.

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

Beta-amyloid precursor protein (APP) and APP-RNA are rapidly affected by glutamate in cultured neurons: selective increase of mRNAs encoding a Kunitz protease inhibitor domain. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

author name string

D A Willoughby

1

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

I Rozovsky

2

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

A C Lo

3

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

C E Finch

4

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

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1 reference

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publication date

1 January 1995

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

Journal of Molecular Neuroscience

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

6

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

4

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

257-276

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

https://scigraph.springernature.com/pub.10.1007/bf02736785

0 references

The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.

1 reference

https://api.crossref.org/works/10.1007%2FBF02736785

21 January 2018

Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid beta-protein precursor-like protein-2.

1 reference

https://api.crossref.org/works/10.1007%2FBF02736785

21 January 2018

Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards an improved serum-free, chemically defined medium for long-term culturing of cerebral cortex tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A family of AMPA-selective glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paradoxical potentiation by low extracellular Ca2+ of acute chemical anoxic neuronal injury in cerebellar granule cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sequence of the two extra exons in rat preA4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketamine, phencyclidine, and MK-801 protect against kainic acid-induced seizure-related brain damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor-like protein 2 (APLP2) is modified by the addition of chondroitin sulfate glycosaminoglycan at a single site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin active site regions required for fibroblast receptor binding and initiation of cell division.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA Antagonist Neurotoxicity: Mechanism and Prevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Alzheimer's amyloid precursor protein is produced by type I astrocytes in primary cultures of rat neuroglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible oxidation of glyceraldehyde 3-phosphate dehydrogenase thiols in human lung carcinoma cells by hydrogen peroxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein mRNA stability is controlled by a 29-base element in the 3'-untranslated region

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta A4-amyloid protein precursor mRNA isoforms without exon 15 are ubiquitously expressed in rat tissues including brain, but not in neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decrease in amyloid precursor protein precedes hippocampal degeneration in rat brain following transient global ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of beta-amyloid protein deposits in brains of transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxins in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing of beta-amyloid precursor by calpain I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased neuronal beta-amyloid precursor protein expression in human temporal lobe epilepsy: association with interleukin-1 alpha immunoreactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine hydroxylase mRNA expression by dopaminergic neurons in culture: effect of 1-methyl-4-phenylpyridinium treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of glutamate in epilepsy and other CNS disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased β-Amyloid Precursor Protein Expression in Astrocytes in the Gerbil Hippocampus Following Ischaemia: Association with Proliferation of Astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate neurotoxicity in cortical cell culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular specificity and regional distribution of amyloid beta protein precursor alternative transcripts are unaltered in Alzheimer hippocampal formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the amyloid precursor-like protein 2 in MDCK cells. Polarized trafficking occurs independent of the chondroitin sulfate glycosaminoglycan chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential splicing of Alzheimer's disease amyloid A4 precursor RNA in rat tissues: PreA4(695) mRNA is predominantly produced in rat and human brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular localization and laminar distribution of NMDAR1 mRNA in the rat cerebral cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular diversity of glutamate receptors and implications for brain function

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of beta-amyloid precursor protein in reactive astrocytes following neuronal damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lactic dehydrogenase activity in blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice expressing human beta-APP751, but not mice expressing beta-APP695, display early Alzheimer's disease-like histopathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein mRNA encoding the Kunitz protease inhibitor domain is increased by kainic acid-induced seizures in rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuron-specific splicing of the Alzheimer amyloid precursor protein gene in a mini-gene system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks beta/A4 amyloid immunoreactivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody to beta-amyloid precursor protein recognizes an intermediate filament-associated protein in Alzheimer's and control fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/8860237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF02736785

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

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release_rgauemom5jfjtb3txkcqshqoya

1 reference

https://api.fatcat.wiki/v0/release/rgauemom5jfjtb3txkcqshqoya

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/8860237

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