(Q45982085)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19497963%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Urokinase activates macrophage PON2 gene transcription via the PI3K/ROS/MEK/SREBP-2 signalling cascade mediated by the PDGFR-beta (English)

1 reference

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30 January 2020

1 reference

6

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30 January 2020

author name string

Bianca Fuhrman

1

1 reference

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30 January 2020

Anna Gantman

2

1 reference

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30 January 2020

Jasmin Khateeb

3

1 reference

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30 January 2020

Nina Volkova

4

1 reference

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30 January 2020

Sven Horke

5

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30 January 2020

Inna Dumler

7

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30 January 2020

Michael Aviram

8

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30 January 2020

publication date

4 June 2009

1 reference

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30 January 2020

published in

Cardiovascular Research

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30 January 2020

volume

84

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30 January 2020

issue

1

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30 January 2020

page(s)

145-154

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Atherosclerosis — An Inflammatory Disease

30 January 2020

cites work

1 reference

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New insights on oxidative stress in the artery wall.

21 January 2018

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LDL oxidation by arterial wall macrophages depends on the oxidative status in the lipoprotein and in the cells: role of prooxidants vs. antioxidants

21 January 2018

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Increased uptake of LDL by oxidized macrophages is the result of an initial enhanced LDL receptor activity and of a further progressive oxidation of LDL.

21 January 2018

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Oxidative stress increases the expression of the CD36 scavenger receptor and the cellular uptake of oxidized low-density lipoprotein in macrophages from atherosclerotic mice: protective role of antioxidants and of paraoxonase

21 January 2018

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Adenovirus mediated expression of human paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein E-deficient mice

21 January 2018

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Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein

21 January 2018

1 reference

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A biphasic U-shape effect of cellular oxidative stress on the macrophage anti-oxidant paraoxonase 2 (PON2) enzymatic activity

21 January 2018

1 reference

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Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR gamma and AP-1 pathway activation

21 January 2018

1 reference

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Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

Macrophage paraoxonase 2 (PON2) expression is upregulated by unesterified cholesterol through activation of the phosphatidylinositol 3-kinase (PI3K) pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

Decreased Macrophage Paraoxonase 2 Expression in Patients With Hypercholesterolemia Is the Result of Their Increased Cellular Cholesterol Content: Effect of Atorvastatin Therapy

21 January 2018

1 reference

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Urokinase-induced signaling in human vascular smooth muscle cells is mediated by PDGFR-beta

21 January 2018

1 reference

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Nonproteolytic role for the urokinase receptor in cellular migration in vivo.

21 January 2018

1 reference

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Association between plasmin activation system and intravascular ultrasound signs of plaque instability in patients with unstable angina and non-st-segment elevation myocardial infarction.

21 January 2018

1 reference

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Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death

21 January 2018

1 reference

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Urokinase plasminogen activator (uPA) stimulates cholesterol biosynthesis in macrophages through activation of SREBP-1 in a PI3-kinase and MEK-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

Urokinase plasminogen activator upregulates paraoxonase 2 expression in macrophages via an NADPH oxidase-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins

21 January 2018

1 reference

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Cell-induced copper ion-mediated low density lipoprotein oxidation increases during in vivo monocyte-to-macrophage differentiation

21 January 2018

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Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation

21 January 2018

1 reference

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Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: a role for sterol regulatory element-binding protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

Low-density lipoprotein upregulates low-density lipoprotein receptor-related protein expression in vascular smooth muscle cells: possible involvement of sterol regulatory element binding protein-2-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

Differential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

Expression of platelet derived growth factor B chain and beta receptor in human coronary arteries after percutaneous transluminal coronary angioplasty: an immunohistochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVP184

21 January 2018

Identifiers

DOI

10.1093/CVR/CVP184

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19497963%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference