(Q45989293)

18 December 2017

title

Substrate specificity of CDK2-cyclin A. What is optimal? (English)

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18 December 2017

author name string

Lisa M Stevenson-Lindert

series ordinal

1

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18 December 2017

Paul Fowler

series ordinal

2

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18 December 2017

John Lew

series ordinal

3

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18 December 2017

language of work or name

English

0 references

publication date

23 September 2003

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18 December 2017

Journal of Biological Chemistry

published in

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18 December 2017

volume

278

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18 December 2017

issue

51

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18 December 2017

page(s)

50956-50960

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18 December 2017

Substrates for p34cdc2: in vivo veritas?

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1 reference

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A predictive scale for evaluating cyclin-dependent kinase substrates. A comparison of p34cdc2 and p33cdk2.

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Kinetic basis for activation of CDK2/cyclin A by phosphorylation

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Use of an oriented peptide library to determine the optimal substrates of protein kinases

21 January 2018

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21 January 2018

Cyclin-Dependent Kinases

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

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E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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Regulation of chromosome replication

21 January 2018

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Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes

21 January 2018

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Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

21 January 2018

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Mutational analysis of the Cy motif from p21 reveals sequence degeneracy and specificity for different cyclin-dependent kinases

21 January 2018

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Activation mechanism of CDK2: role of cyclin binding versus phosphorylation

21 January 2018

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Catalytic reaction pathway for the mitogen-activated protein kinase ERK2.

21 January 2018

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Investigation of diffusion-limited rates of chymotrypsin reactions by viscosity variation

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MAP kinases and CDKs: kinetic basis for catalytic activation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The design of peptide-based substrates for the cdc2 protein kinase

21 January 2018

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Characterization of synthetic peptide substrates for p34cdc2 protein kinase

21 January 2018

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The role of Thr160 phosphorylation of Cdk2 in substrate recognition

21 January 2018

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Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4

21 January 2018

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DP1 phosphorylation in multimeric complexes: weaker interaction with cyclin A through the E2F1 cyclin A binding domain leads to more efficient phosphorylation than stronger interaction through the p107 cyclin A binding domain.

21 January 2018

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Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs

21 January 2018

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Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins

21 January 2018

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Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

21 January 2018

1 reference

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The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

21 January 2018

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A bipartite substrate recognition motif for cyclin-dependent kinases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M306546200

1 reference

18 December 2017

release_4to57nt5wvedxd22sjbiwl3rgy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4to57nt5wvedxd22sjbiwl3rgy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

18 December 2017