(Q45993589)

18 December 2017

title

Critical role of IL-2 and TGF-beta in generation, function and stabilization of Foxp3+CD4+ Treg. (English)

1 reference

18 December 2017

author name string

David A Horwitz

1

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18 December 2017

Song Guo Zheng

2

1 reference

18 December 2017

Juhua Wang

3

1 reference

18 December 2017

J Dixon Gray

4

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18 December 2017

language of work or name

English

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publication date

1 April 2008

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18 December 2017

European Journal of Immunology

published in

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18 December 2017

volume

38

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18 December 2017

page(s)

912-915

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18 December 2017

issue

4

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18 December 2017

TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

Inducing and expanding regulatory T cell populations by foreign antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

TGFbeta signalling in control of T-cell-mediated self-reactivity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

A function for interleukin 2 in Foxp3-expressing regulatory T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

An essential role for Scurfin in CD4+CD25+ T regulatory cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Dendritic cells are specialized accessory cells along with TGF- for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3 precursors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Endogenous TGF-beta activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200738109

7 January 2021

Identifiers

DOI

10.1002/EJI.200738109

1 reference

18 December 2017

PubMed ID

18395858

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18 December 2017