(Q45996029)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

The calcimimetic AMG 641 abrogates parathyroid hyperplasia, bone and vascular calcification abnormalities in uremic rats (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

main subject

vascular calcification

1 reference

Charles Henley

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

James Davis

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Gerald Miller

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Edward Shatzen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Russ Cattley

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Xiaodong Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

David Martin

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Wei Yao

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Nancy Lane

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Victoria Shalhoub

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

24 May 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Pharmacology

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

616

1 reference

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29 January 2020

issue

1-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

306-313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

Therapeutic use of calcimimetics

29 January 2020

cites work

1 reference

12 December 2020

Calcimimetic compound NPS R-568 stimulates calcitonin secretion but selectively targets parathyroid gland Ca(2+) receptor in rats

1 reference

12 December 2020

Phosphate regulation of vascular smooth muscle cell calcification

1 reference

12 December 2020

Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice

1 reference

12 December 2020

Mortality risk among hemodialysis patients receiving different vitamin D analogs

1 reference

12 December 2020

A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremia

1 reference

12 December 2020

Long-term comparison of a calcium-free phosphate binder and calcium carbonate--phosphorus metabolism and cardiovascular calcification.

1 reference

12 December 2020

Calcimimetic compound upregulates decreased calcium-sensing receptor expression level in parathyroid glands of rats with chronic renal insufficiency.

1 reference

12 December 2020

Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study

1 reference

12 December 2020

Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification

1 reference

12 December 2020

Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism.

1 reference

12 December 2020

Massive soft tissue calcifications and cinacalcet

1 reference

12 December 2020

Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro

1 reference

12 December 2020

Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells

1 reference

12 December 2020

Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro

1 reference

12 December 2020

The calcimimetic R-568 increases vitamin D receptor expression in rat parathyroid glands

1 reference

12 December 2020

Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis

1 reference

12 December 2020

A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.

1 reference

12 December 2020

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

1 reference

12 December 2020

The calcium-sensing receptor: a key factor in the pathogenesis of secondary hyperparathyroidism.

1 reference

12 December 2020

Rat calcium-sensing receptor is regulated by vitamin D but not by calcium.

1 reference

12 December 2020

Effects of the calcimimetic cinacalcet HCl on cardiovascular disease, fracture, and health-related quality of life in secondary hyperparathyroidism

1 reference

12 December 2020

1,25-Dihydroxyvitamin D3 but not cinacalcet HCl (Sensipar/Mimpara) treatment mediates aortic calcification in a rat model of secondary hyperparathyroidism

1 reference

12 December 2020

Arteriosclerosis, vascular calcifications and cardiovascular disease in uremia

1 reference

12 December 2020

Effects of calcitriol on parathyroid function and on bone remodelling in secondary hyperparathyroidism

1 reference

12 December 2020

Cinacalcet suppresses calcification of the aorta and heart in uremic rats

1 reference

12 December 2020

Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25-dihydroxy-cholecalciferol in uremic patients

1 reference

12 December 2020

The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor

1 reference

12 December 2020

Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients

1 reference

12 December 2020

Effects of cinacalcet on bone mineral density in patients with secondary hyperparathyroidism

1 reference

12 December 2020

p21WAF1 and TGF-alpha mediate parathyroid growth arrest by vitamin D and high calcium

1 reference

12 December 2020

1,25(OH)2 vitamin D3 inhibits parathyroid cell proliferation in experimental uremia

1 reference

12 December 2020

Calcimimetic R-568 or calcitriol: equally beneficial on progression of renal damage in subtotally nephrectomized rats.

1 reference

12 December 2020

Calcification inhibitors and Wnt signaling proteins are implicated in bovine artery smooth muscle cell calcification in the presence of phosphate and vitamin D sterols

1 reference

12 December 2020

Calcimimetic NPS R-568 prevents parathyroid hyperplasia in rats with severe secondary hyperparathyroidism

1 reference

12 December 2020

Calcification and cardiovascular problems in renal failure

1 reference

12 December 2020

Activation of the calcium receptor by a calcimimetic compound halts the progression of secondary hyperparathyroidism in uremic rats

1 reference

12 December 2020

Severe hyperparathyroidism with bone abnormalities and metastatic calcification in rats with adenine-induced uraemia.

1 reference

12 December 2020

Pharmacodynamics of the Type II Calcimimetic Compound Cinacalcet HCl

1 reference

12 December 2020

NPS R-568 halts or reverses osteitis fibrosa in uremic rats

1 reference

12 December 2020

Intravenous calcitriol in the treatment of refractory osteitis fibrosa of chronic renal failure

1 reference

12 December 2020

Studies in a hemodialysis patient indicating that calcitriol may have a direct suppressive effect on bone

1 reference

12 December 2020

Impact of high coronary artery calcification score (CACS) on survival in patients on chronic hemodialysis.

1 reference

12 December 2020

Calcimimetic R-568 decreases extraosseous calcifications in uremic rats treated with calcitriol.

1 reference

12 December 2020

Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients

1 reference

12 December 2020

Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients

1 reference

12 December 2020

The fallacy of the calcium-phosphorus product

1 reference

12 December 2020

Vascular calcification in chronic kidney disease

1 reference

12 December 2020

The effect of calcitriol, paricalcitol, and a calcimimetic on extraosseous calcifications in uremic rats

1 reference

12 December 2020

Secondary hyperparathyroidism: review of the disease and its treatment.

1 reference

12 December 2020

Predictors and consequences of altered mineral metabolism: the Dialysis Outcomes and Practice Patterns Study

1 reference

12 December 2020

Development and progression of secondary hyperparathyroidism in chronic kidney disease: lessons from molecular genetics

1 reference

12 December 2020

Animal model of adenine-induced chronic renal failure in rats

1 reference

12 December 2020

Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis

1 reference

12 December 2020

The calcium-sensing receptor: a window into the physiology and pathophysiology of mineral ion metabolism

1 reference

12 December 2020

Extracellular calcium sensing and extracellular calcium signaling

1 reference

12 December 2020

Can calcimimetics inhibit parathyroid hyperplasia? Evidence from preclinical studies

1 reference

12 December 2020

10.1016/J.EJPHAR.2009.05.013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19470383%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference