(Q45998535)

18 December 2017

title

PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity. (English)

1 reference

18 December 2017

author name string

Angus J M Cameron

1

1 reference

18 December 2017

Cristina Escribano

2

1 reference

18 December 2017

Adrian T Saurin

3

1 reference

18 December 2017

Brenda Kostelecky

4

1 reference

18 December 2017

Peter J Parker

5

1 reference

18 December 2017

publication date

24 May 2009

1 reference

18 December 2017

Nature Structural & Molecular Biology

published in

1 reference

18 December 2017

volume

16

1 reference

18 December 2017

page(s)

624-630

1 reference

18 December 2017

issue

6

1 reference

18 December 2017

https://scigraph.springernature.com/pub.10.1038/nsmb.1606

exact match

0 references

cites work

Multiple pathways control protein kinase C phosphorylation

1 reference

A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

21 January 2018

1 reference

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation

21 January 2018

1 reference

The extended protein kinase C superfamily

21 January 2018

1 reference

Association of immature hypophosphorylated protein kinase cepsilon with an anchoring protein CG-NAP

21 January 2018

1 reference

The hydrophobic phosphorylation motif of conventional protein kinase C is regulated by autophosphorylation

21 January 2018

1 reference

Regulation of novel protein kinase C epsilon by phosphorylation.

21 January 2018

1 reference

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

21 January 2018

1 reference

Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha.

21 January 2018

1 reference

Magic bullets for protein kinases

21 January 2018

1 reference

The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily

21 January 2018

1 reference

Protein kinase C epsilon regulates gamma-aminobutyrate type A receptor sensitivity to ethanol and benzodiazepines through phosphorylation of gamma2 subunits

21 January 2018

1 reference

Emerging roles of pseudokinases

21 January 2018

1 reference

PKC alpha protein but not kinase activity is critical for glioma cell proliferation and survival

21 January 2018

1 reference

The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A.

21 January 2018

1 reference

Crystal structure of an inactive Akt2 kinase domain

21 January 2018

1 reference

Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP-PNP

21 January 2018

1 reference

The structure of MSK1 reveals a novel autoinhibitory conformation for a dual kinase protein.

21 January 2018

1 reference

Structure of the catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor

21 January 2018

1 reference

Crystal structure of the catalytic domain of human atypical protein kinase C-iota reveals interaction mode of phosphorylation site in turn motif

21 January 2018

1 reference

Catalytic domain crystal structure of protein kinase C-theta (PKCtheta).

21 January 2018

1 reference

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

21 January 2018

1 reference

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

21 January 2018

1 reference

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

Dephosphorylation of PKCdelta by protein phosphatase 2Ac and its inhibition by nucleotides

21 January 2018

1 reference

Bypassing a Kinase Activity with an ATP-Competitive Drug

21 January 2018

1 reference

Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon

21 January 2018

1 reference

Multisite dephosphorylation and desensitization of conventional protein kinase C isotypes

21 January 2018

1 reference

The regulated assembly of a PKCepsilon complex controls the completion of cytokinesis

21 January 2018

1 reference

The role of protein kinase C in cell surface signal transduction and tumour promotion

21 January 2018

2 references

21 January 2018

12 December 2020

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

Phosphorylation of protein kinase C-alpha on serine 657 controls the accumulation of active enzyme and contributes to its phosphatase-resistant state

31 March 2020

1 reference

Loss of protein kinase C function induces an apoptotic response

31 March 2020

1 reference

Irreversible oxidative inactivation of protein kinase C by photosensitive inhibitor calphostin C

31 March 2020

1 reference

A point mutation at the putative ATP-binding site of protein kinase C alpha abolishes the kinase activity and renders it down-regulation-insensitive. A molecular link between autophosphorylation and down-regulation

31 March 2020

1 reference

PubMed

12 December 2020

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

1 reference

PubMed

12 December 2020

Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1038/NSMB.1606

1 reference

18 December 2017

Dimensions Publication ID

0 references

1 reference

18 December 2017