(Q46002885)

English

Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/16870742

Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

cerebral infarction

1 reference

based on heuristic

inferred from title

author name string

Hidenori Endo

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

Hiroshi Kamada

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

Chikako Nito

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

Tatsuro Nishi

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

Pak H Chan

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

language of work or name

0 references

publication date

1 July 2006

1 reference

Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/16870742

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

26

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

7974-7983

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

30

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumor suppressor p53 and its response gene p21WAF1/Cip1 are not markers of neuronal death following transient global cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of p53 and its target genes p21(WAF1/Cip1) and PAG608/Wig-1 in ischemic preconditioning.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PUMA induces the rapid apoptosis of colorectal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: protective role of a p53 inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 has a direct apoptogenic role at the mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 downstream targets and chemosensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of GRP78 by ischemic preconditioning reduces endoplasmic reticulum stress and prevents delayed neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal inhibition of p53 and nuclear factor-kappaB transcriptional activities determines cell survival or death in neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative Damage to the Endoplasmic Reticulum is Implicated in Ischemic Neuronal Cell Death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of p53-induced apoptosis in cerebral ischemia: effects of the p53 inhibitor pifithrin alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 potentiates hippocampal neuronal death caused by global ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed neuronal death in the gerbil hippocampus following ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic delayed neuronal death. A mitochondrial hypothesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxidants in ischemic brain damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for p53-mediated modulation of neuronal viability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53, the cellular gatekeeper for growth and division

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of CuZn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bax involvement in p53-mediated neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16870742

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0897-06.2006

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674216&resulttype=core&format=json

11 May 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46002885&oldid=1397781035"