(Q46003997)

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Aldose reductase regulates hepatic peroxisome proliferator-activated receptor alpha phosphorylation and activity to impact lipid homeostasis.

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

Aldose reductase regulates hepatic peroxisome proliferator-activated receptor alpha phosphorylation and activity to impact lipid homeostasis. (English)

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

phosphorylation

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author name string

Longxin Qiu

1

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

Xiaochun Wu

2

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

Jenny F L Chau

3

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/18445591

Irene Y Y Szeto

4

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/18445591

Wing Yip Tam

5

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/18445591

Zongsheng Guo

6

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/18445591

Sookja K Chung

7

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/18445591

Peter J Oates

8

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

Stephen S M Chung

9

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/18445591

James Y Yang

10

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18 December 2017

http://europepmc.org/abstract/MED/18445591

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29 April 2008

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

283

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

25

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

17175-17183

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

Polyol pathway and diabetic peripheral neuropathy

1 reference

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Increased fructose concentrations in blood and urine in patients with diabetes

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Plasma and red cell sorbitol assay in diabetic subjects.

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Clinical usefulness of measuring urinary polyol excretion by gas-chromatography/mass-spectrometry in type 2 diabetes to assess polyol pathway activity

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Tissue distribution of mammalian aldose reductase and related enzymes

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The distribution of polyol: NADP oxidoreductase in mammalian tissues

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Enzyme relationships in a sorbitol pathway that bypasses glycolysis and pentose phosphates in glucose metabolism

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Identification and characterization of a novel human aldose reductase-like gene

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New member of aldose reductase family proteins overexpressed in human hepatocellular carcinoma

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Detection and identification of tumor-associated protein variants in human hepatocellular carcinomas

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Overexpression of aldose reductase in liver cancers may contribute to drug resistance

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Induction of aldose reductase gene expression in LEC rats during the development of the hereditary hepatitis and hepatoma.

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Impairment of hepatic Stat-3 activation and reduction of PPARalpha activity in fructose-fed rats

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PPARalpha and dyslipidemia

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ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand

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21 January 2018

Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth.

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21 January 2018

Aldose reductase-deficient mice develop nephrogenic diabetes insipidus

1 reference

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21 January 2018

Cloning, Sequencing, and Determination of the Sites of Expression of Mouse Sorbitol Dehydrogenase cDNA

1 reference

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21 January 2018

Modulation of PPAR activity via phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801791200

21 January 2018

Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor alpha by phosphorylation of a ligand-independent trans-activating domain

1 reference

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21 January 2018

Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth

1 reference

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21 January 2018

Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor alpha by dehydroepiandrosterone and other peroxisome proliferators

1 reference

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21 January 2018

Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators

1 reference

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21 January 2018

Biochemistry and molecular cell biology of diabetic complications

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21 January 2018

Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice

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21 January 2018

Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice.

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21 January 2018

Aldose reductase, still a compelling target for diabetic neuropathy

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21 January 2018

Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis

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21 January 2018

A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice.

1 reference

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21 January 2018

Transcriptional control of triglyceride metabolism: fibrates and fatty acids change the expression of the LPL and apo C-III genes by activating the nuclear receptor PPAR.

1 reference

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21 January 2018

Kinase signaling cascades that modulate peroxisome proliferator-activated receptors

1 reference

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21 January 2018

Protein kinase C activation and the development of diabetic complications

1 reference

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21 January 2018

The transcription of the peroxisome proliferator-activated receptor alpha gene is regulated by protein kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801791200

21 January 2018

Regulation of peroxisome proliferator-activated receptor alpha by protein kinase C.

1 reference

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21 January 2018

The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha

1 reference

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21 January 2018

A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders

1 reference

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21 January 2018

WY 14,643 inhibits human aldose reductase activity

1 reference

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21 January 2018

Fibrates inhibit aldose reductase activity in the forward and reverse reactions

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M801791200

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/18445591

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