(Q46030445)

English

Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin.

scientific article published in May 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

author name string

Yu-Si Cheng

1

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

De-Zai Dai

2

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

Yin Dai

3

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

publication date

1 May 2009

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

Journal of Pharmacy and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

61

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

5

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

569-576

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: a biochemical and histoarchitectural evaluation

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Endothelin receptor antagonist CPU0213 and vitamin E reverse downregulation of FKBP12.6 and SERCA2a: a role of hyperphosphorylation of PKCepsilon

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Ryanodine receptor-targeted anti-arrhythmic therapy

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU86017.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Downregulated FKBP12.6 expression and upregulated endothelin signaling contribute to elevated diastolic calcium and arrhythmogenesis in rat cardiomyopathy produced by l-thyroxin

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Role of inflammation and oxidative stress in endothelial progenitor cell function and mobilization: therapeutic implications for cardiovascular diseases

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Cardiac oxidative stress in acute and chronic isoproterenol-infused rats

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Improvement of chronic heart failure by dexamethasone is not associated with downregulation of leptin in rats

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Effect of the endothelin receptor antagonist CPU0213, and its modulation by rifampin, on cardiac and vascular tissue following chronic isoproterenol treatment

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Tonic beta-adrenergic drive provokes proinflammatory and proapoptotic changes in aging mouse heart

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Could Beta blockade improve outcome after injury by modulating inflammatory profiles?

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Endothelium-derived nitric oxide mediates the antiadrenergic effect of human vasostatin-1 in rat ventricular myocardium

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Leptin and hypertension in obesity

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS).

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Leptin protects the cardiac myocyte cultures from hypoxic damage

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Leptin regulates cardiomyocyte contractile function through endothelin-1 receptor-NADPH oxidase pathway

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Endogenous endothelin in human coronary vascular function: differential contribution of endothelin receptor types A and B.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Reversal of cardiac dysfunction by selective ET-A receptor antagonism

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

The antibiotic erythromycin induces tolerance against transient global cerebral ischemia in rats (pharmacologic preconditioning).

1 reference

https://api.crossref.org/works/10.1211%2FJPP.61.05.0004

21 January 2018

Identifiers

10.1211/JPP.61.05.0004

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19405994

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