(Q46033964)

18 December 2017

title

Proteasome inhibitor MG132 inhibits angiogenesis in pancreatic cancer by blocking NF-kappaB activity. (English)

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18 December 2017

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Yoichi Matsuo

1

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18 December 2017

Hirozumi Sawai

2

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18 December 2017

Nobuo Ochi

3

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18 December 2017

Akira Yasuda

4

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18 December 2017

Masaki Sakamoto

5

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18 December 2017

Hiroki Takahashi

6

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18 December 2017

Hitoshi Funahashi

7

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18 December 2017

Hiromitsu Takeyama

8

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18 December 2017

Sushovan Guha

9

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18 December 2017

publication date

28 April 2009

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18 December 2017

Digestive Diseases and Sciences

published in

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18 December 2017

volume

55

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18 December 2017

issue

4

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18 December 2017

page(s)

1167-1176

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18 December 2017

https://scigraph.springernature.com/pub.10.1007/s10620-009-0814-4

exact match

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cites work

Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10620-009-0814-4

Proteasome inhibitor MG132 reverses multidrug resistance of gastric cancer through enhancing apoptosis and inhibiting P-gp

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10620-009-0814-4

Enhanced expression of vascular endothelial growth factor in human pancreatic cancer correlates with local disease progression

21 January 2018

1 reference

12 December 2020

The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells

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12 December 2020

Interleukin-8 and human cancer biology

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12 December 2020

The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis

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12 December 2020

Targeting BCL-2 overexpression in various human malignancies through NF-kappaB inhibition by the proteasome inhibitor bortezomib

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12 December 2020

Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

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12 December 2020

Pancreaticoduodenectomy for cancer of the head of the pancreas. 201 patients

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12 December 2020

Interleukin-1alpha secreted by pancreatic cancer cells promotes angiogenesis and its therapeutic implications

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12 December 2020

Enhanced angiogenesis due to inflammatory cytokines from pancreatic cancer cell lines and relation to metastatic potential

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12 December 2020

How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes memorial Award lecture

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12 December 2020

Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription.

1 reference

12 December 2020

The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts.

1 reference

12 December 2020

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

1 reference

12 December 2020

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

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12 December 2020

Molecular mechanisms of blood vessel formation

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12 December 2020

Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells.

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12 December 2020

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

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12 December 2020

NF-kappaB activity blockade impairs the angiogenic potential of human pancreatic cancer cells

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12 December 2020

Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells

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12 December 2020

What Is the Evidence That Tumors Are Angiogenesis Dependent?

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12 December 2020

Novel therapies for pancreatic adenocarcinoma

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12 December 2020

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract

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12 December 2020

Advances in the diagnosis and treatment of adenocarcinoma of the pancreas

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12 December 2020

Cardiac-specific activation of signal transducer and activator of transcription 3 promotes vascular formation in the heart.

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12 December 2020

HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

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12 December 2020

The microenvironment of the tumour-host interface

1 reference

12 December 2020

Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic.

1 reference

12 December 2020

Interleukin-1alpha enhances IL-8 secretion through p38 mitogen-activated protein kinase and reactive oxygen species signaling in human pancreatic cancer cells.

1 reference

12 December 2020

PS-341 and gemcitabine in patients with metastatic pancreatic adenocarcinoma: a North Central Cancer Treatment Group (NCCTG) randomized phase II study

1 reference

12 December 2020

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

12 December 2020

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

1 reference

12 December 2020

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

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12 December 2020

Inhibition of proteasome function induced apoptosis in gastric cancer.

1 reference

12 December 2020

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

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12 December 2020

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

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12 December 2020

NF-kappaB in cancer: from innocent bystander to major culprit

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12 December 2020

An in vitro model of angiogenesis: basic features

1 reference

12 December 2020

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

1 reference

12 December 2020

The proteasome inhibitor MG132 induces apoptosis in human pancreatic cancer cells.

1 reference

12 December 2020

Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

1 reference

12 December 2020

Angiogenesis and angiogenesis inhibition: an overview

1 reference

12 December 2020

Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer

1 reference

12 December 2020

Molecular regulation of constitutive expression of interleukin-8 in human pancreatic adenocarcinoma

1 reference

12 December 2020

Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts.

1 reference

12 December 2020

Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma

1 reference

12 December 2020

10.1007/S10620-009-0814-4

Identifiers

DOI

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18 December 2017

PubMed ID

19399612

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18 December 2017