(Q46035750)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Glucose inhibits the insulin-induced activation of the insulin-degrading enzyme in HepG2 cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Andreas Pfeiffer

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

O Gögebakan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

N Rudovich

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

25 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

1656-1664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19396426%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00125-009-1350-7

26 January 2020

exact match

0 references

cites work

Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-009-1350-7

Insulin degrading enzyme activity and insulin binding of erythrocytes in normal subjects and Type 2 (non-insulin-dependent) diabetic patients.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-009-1350-7

The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes.

21 January 2018

1 reference

12 December 2020

Relationship between insulin-degrading enzyme activity and insulin sensitivity in cell model of insulin-resistance

1 reference

12 December 2020

A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study

1 reference

12 December 2020

Effect of insulin and glucose on the activity of insulin-degrading enzymes in rat liver

1 reference

12 December 2020

Fluoride and phosphatidylserine induced inhibition of cytosolic insulin-degrading activity

1 reference

12 December 2020

Association of polymorphisms in the insulin-degrading enzyme gene with type 2 diabetes in the Korean population.

1 reference

12 December 2020

Insulin inhibits the ubiquitin-dependent degrading activity of the 26S proteasome

1 reference

12 December 2020

Insulin inhibits peroxisomal fatty acid oxidation in isolated rat hepatocytes

1 reference

12 December 2020

Defects in insulin-receptor internalization and processing in monocytes of obese subjects and obese NIDDM patients

1 reference

12 December 2020

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study

1 reference

12 December 2020

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

1 reference

12 December 2020

Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues

1 reference

12 December 2020

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

1 reference

12 December 2020

Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families

1 reference

12 December 2020

Enzyme target to latch on to

1 reference

12 December 2020

[Insulin degradation in hepatocytes and erythrocytes of rats in normal condition and in experimental diabetes]

1 reference

12 December 2020

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

1 reference

12 December 2020

An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures

1 reference

12 December 2020

AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells

1 reference

12 December 2020

Pathogenesis of type 2 (non-insulin dependent) diabetes mellitus: a balanced overview

1 reference

12 December 2020

Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development.

1 reference

12 December 2020

ATP effects on insulin-degrading enzyme are mediated primarily through its triphosphate moiety

1 reference

12 December 2020

Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.

1 reference

12 December 2020

Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver

1 reference

12 December 2020

Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis.

1 reference

12 December 2020

Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein

1 reference

12 December 2020

Androgen and glucocorticoid receptors interact with insulin degrading enzyme.

1 reference

12 December 2020

Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels

1 reference

12 December 2020

Immunoreactive insulin and insulin degrading enzymes in erythrocytes. A preliminary report.

1 reference

12 December 2020

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

12 December 2020

The Metabolism of Proinsulin and Insulin by the Liver

1 reference

12 December 2020

Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

1 reference

12 December 2020

Insulin-degrading neutral cysteine proteinase activity of adipose tissue and liver of nondiabetic, streptozotocin-diabetic, and insulin-treated diabetic rats

1 reference

12 December 2020

Insulin-degrading enzyme hydrolyzes ATP

1 reference

12 December 2020

Reduced hepatic insulin extraction in response to gastric inhibitory polypeptide compensates for reduced insulin secretion in normal-weight and normal glucose tolerant first-degree relatives of type 2 diabetic patients

1 reference

12 December 2020

Decreased hepatic insulin extraction in subjects with mild glucose intolerance.

1 reference

12 December 2020

Non-covalent interaction of ubiquitin with insulin-degrading enzyme

1 reference

12 December 2020

Hyperinsulinemia in african-american children: decreased insulin clearance and increased insulin secretion and its relationship to insulin sensitivity

1 reference

12 December 2020

Overexpression of insulin degrading enzyme: cellular localization and effects on insulin signaling

1 reference

12 December 2020

In VitroInhibition of Insulin-Degrading Enzyme by Long-Chain Fatty Acids and Their Coenzyme A Thioesters

1 reference

12 December 2020

Insulin degradation: progress and potential

1 reference

12 December 2020

Regulation of protein degradation by insulin-degrading enzyme: analysis by small interfering RNA-mediated gene silencing

1 reference

12 December 2020