(Q46038344)

English

Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting.

scientific article published on 24 April 2009

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scholarly article

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Europe PubMed Central

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26 January 2020

Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting (English)

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26 January 2020

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1 reference

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Birte Yding Glenthøj

2

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26 January 2020

author name string

Brian Villumsen Broberg

1

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26 January 2020

Rebecca Dias

3

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26 January 2020

Dorrit Bjerg Larsen

4

1 reference

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26 January 2020

Christina Kurre Olsen

5

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26 January 2020

publication date

24 April 2009

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26 January 2020

Psychopharmacology

1 reference

Europe PubMed Central

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26 January 2020

206

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26 January 2020

4

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26 January 2020

631-640

1 reference

Europe PubMed Central

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26 January 2020

https://scigraph.springernature.com/pub.10.1007/s00213-009-1540-5

0 references

Recent advances in the phencyclidine model of schizophrenia

1 reference

https://api.crossref.org/works/10.1007%2FS00213-009-1540-5

21 January 2018

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

1 reference

https://api.crossref.org/works/10.1007%2FS00213-009-1540-5

21 January 2018

What are the functional consequences of neurocognitive deficits in schizophrenia?

1 reference

https://api.crossref.org/works/10.1007%2FS00213-009-1540-5

21 January 2018

Adrenarche in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A placebo-controlled add-on trial of the Ampakine, CX516, for cognitive deficits in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of haloperidol, risperidone, sertindole, and modafinil to reverse an attentional set-shifting impairment following subchronic PCP administration in the rat--a back translational study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A drug that facilitates glutamatergic transmission reduces exploratory activity and improves performance in a learning-dependent task

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primate analogue of the Wisconsin Card Sorting Test: effects of excitotoxic lesions of the prefrontal cortex in the marmoset.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early brain development disruption from NMDA receptor hypofunction: relevance to schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary experience with an ampakine (CX516) as a single agent for the treatment of schizophrenia: a case series

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translating developmental time across mammalian species.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A centrally active drug that modulates AMPA receptor gated currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement by an ampakine of memory encoding in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of acute and subchronic administration on phencyclidine-induced neurodegeneration in the perinatal rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of AMPA receptor modulators on hippocampal and cortical function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary evidence for an association between minor physical anomalies and second trimester neurodevelopment in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodevelopmental consequences of early exposure to phencyclidine and related drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptor facilitation accelerates fear learning without altering the level of conditioned fear acquired.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facilitative effects of the ampakine CX516 on short-term memory in rats: correlations with hippocampal neuronal activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subchronic phencyclidine administration reduces mesoprefrontal dopamine utilization and impairs prefrontal cortical-dependent cognition in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of low-dose risperidone and low-dose zuclopenthixol on cognitive functions in first-episode drug-naive schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of metabolic hypofunction and neurochemical deficits after chronic intermittent exposure to phencyclidine: differential modulation by antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PCP: from pharmacology to modelling schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation in prefrontal cortex of affective and attentional shifts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facilitation of olfactory learning by a modulator of AMPA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facilitative effects of the ampakine CX516 on short-term memory in rats: enhancement of delayed-nonmatch-to-sample performance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aged rats are impaired on an attentional set-shifting task sensitive to medial frontal cortex damage in young rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic potential of positive AMPA modulators and their relationship to AMPA receptor subunits. A review of preclinical data

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Network interactions in schizophrenia - therapeutic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Study of a new schizophrenomimetic drug; sernyl.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Medial frontal cortex mediates perceptual attentional set shifting in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-based therapeutic approaches: ampakines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Centrally active modulators of glutamate receptors facilitate the induction of long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Medicine. What are the right targets for psychopharmacology?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that a positive modulator of AMPA-type glutamate receptors improves delayed recall in aged humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Child development risk factors for adult schizophrenia in the British 1946 birth cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of a neurodevelopmental model of schizophrenia--early postnatal PCP treatment in attentional set-shifting.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Course of recovery of cognitive impairment in patients with schizophrenia: a randomised double-blind study comparing sertindole and haloperidol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The emerging role of glutamate in the pathophysiology and treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cognitive functioning related to quality of life in schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A placebo-controlled pilot study of the ampakine CX516 added to clozapine in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizophrenia drug says goodbye to dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of ampakine modulators: from AMPA receptors to synapses and behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/19390843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-009-1540-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390843%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390843%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

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