(Q46040085)

18 December 2017

title

Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. (English)

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18 December 2017

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A Valencia

1

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18 December 2017

J Román-Gómez

2

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18 December 2017

J Cervera

3

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18 December 2017

E Such

4

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18 December 2017

E Barragán

5

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18 December 2017

P Bolufer

6

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18 December 2017

F Moscardó

7

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18 December 2017

G F Sanz

8

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18 December 2017

M A Sanz

9

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18 December 2017

publication date

23 April 2009

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18 December 2017

published in

Leukemia

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18 December 2017

volume

23

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18 December 2017

issue

9

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18 December 2017

page(s)

1658-1666

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/leu.2009.86

exact match

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Secreted antagonists of the Wnt signalling pathway

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Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

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Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

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CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia

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Preferential methylation of Wnt inhibitory factor-1 in acute promyelocytic leukemia: an independent poor prognostic factor

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Preferential hypermethylation of the Dickkopf-1 promoter in core-binding factor leukaemia

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Epigenetic inactivation of secreted Frizzled-related proteins in acute myeloid leukaemia

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Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

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Transcriptional silencing of the Dickkopfs-3 (Dkk-3) gene by CpG hypermethylation in acute lymphoblastic leukaemia

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Promoter hypermethylation of cancer-related genes: a strong independent prognostic factor in acute lymphoblastic leukemia.

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Epigenetic inactivation of the secreted frizzled-related protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis

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SARPs: a family of secreted apoptosis-related proteins

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Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

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Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

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DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

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5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.

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7 January 2021

Identifiers

DOI

10.1038/LEU.2009.86

1 reference

18 December 2017

1 reference

18 December 2017