(Q46043181)

English

Inhibition of fatty acid synthase by Orlistat accelerates gastric tumor cell apoptosis in culture and increases survival rates in gastric tumor bearing mice in vivo

scientific article published on 21 April 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

Inhibition of fatty acid synthase by Orlistat accelerates gastric tumor cell apoptosis in culture and increases survival rates in gastric tumor bearing mice in vivo (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

0 references

author name string

Shawn Dowling

1

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

James Cox

2

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

Richard J Cenedella

3

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

publication date

21 April 2009

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

44

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

6

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

489-498

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

https://scigraph.springernature.com/pub.10.1007/s11745-009-3298-2

0 references

Sulindac causes rapid regression of preexisting tumors in Min/+ mice independent of prostaglandin biosynthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of fluorescently labeled caspase inhibitors as affinity labels to detect activated caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HPLC analysis of orlistat and its application to drug quality control studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid synthase and cancer: new application of an old pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orlistat: from antiobesity drug to anticancer agent in Her-2/neu (erbB-2)-overexpressing gastrointestinal tumors?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absolute rates of sterol synthesis estimated from [3H]water for bovine lens epithelial cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-obesity agent Orlistat is associated to increase in colonic preneoplastic markers in rats treated with a chemical carcinogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fatty acid synthase blockade induces tumor cell-cycle arrest by down-regulating Skp2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse models of gastrointestinal tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid synthase expression defines distinct molecular signatures in prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of three human gastric cancer cell lines, NU-GC-2, NU-GC-3 and NU-GC-4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of rapid membrane internalization and recycling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of caveolin-1 in bovine lens and redistribution in cultured bovine lens epithelial cells upon confluence

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of caspases activation in situ by fluorochrome-labeled inhibitors of caspases (FLICA).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19381703

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11745-009-3298-2

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19381703

ResearchGate publication ID

0 references

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