(Q46045008)

English

Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones

scientific article published in June 2009

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scholarly article

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones (English)

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

1 reference

based on heuristic

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author name string

Seong Hwan Hwahng

1

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

Sung Hwan Ki

2

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

Eun Ju Bae

3

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

Hyun Eun Kim

4

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

Sang Geon Kim

5

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

language of work or name

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publication date

1 June 2009

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

49

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

6

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

1913-1925

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

1 reference

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Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

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Putative metabolic effects of the liver X receptor (LXR).

1 reference

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7 January 2021

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.

1 reference

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The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

1 reference

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7 January 2021

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Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

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7 January 2021

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TSC2 mediates cellular energy response to control cell growth and survival

1 reference

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Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein-mediated stellate cell inactivation

1 reference

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7 January 2021

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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

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Identification of a novel class of dithiolethiones that prevent hepatic insulin resistance via the adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Autoregulation of the human liver X receptor alpha promoter

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of p70 s6 kinase by kinase activity of FRAP in vivo

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

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Abrogation of hyperosmotic impairment of insulin signaling by a novel class of 1,2-dithiole-3-thiones through the inhibition of S6K1 activation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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inferred from DOI database lookup

Mechanisms of chemoprotection by oltipraz

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

The nuclear receptor LXR is a glucose sensor

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

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Mapping of phosphorylation sites by a multi-protease approach with specific phosphopeptide enrichment and NanoLC-MS/MS analysis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.22887

7 January 2021

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Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

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The LKB1 tumor suppressor negatively regulates mTOR signaling

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Role of AMP-activated protein kinase in mechanism of metformin action

1 reference

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Metformin reverses fatty liver disease in obese, leptin-deficient mice

1 reference

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miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

1 reference

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Liver X receptors interact with corepressors to regulate gene expression

1 reference

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New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

1 reference

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Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

1 reference

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Pharmacokinetic changes of oltipraz after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine

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Identifiers

10.1002/HEP.22887

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19378344

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