(Q46047486)

19 December 2017

title

Structure and parameterization of pharmacokinetic models: their impact on model predictions (English)

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19 December 2017

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2

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19 December 2017

Robert Spear

series ordinal

4

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19 December 2017

author name string

Woodruff TJ

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1

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19 December 2017

Auslander D

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3

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19 December 2017

publication date

1 June 1992

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19 December 2017

published in

Risk Analysis

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19 December 2017

volume

12

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19 December 2017

issue

2

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19 December 2017

page(s)

189-201

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19 December 2017

Risk assessment extrapolations and physiological modeling.

cites work

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https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

Mechanisms of benzene carcinogenesis: application of a physiological model of benzene pharmacokinetics and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

A physiological model for simulation of benzene metabolism by rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

Pharmacokinetics of benzene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

A comparative study of the effects of benzene, toluene, and xylenes on their in vitro metabolism and drug-metabolizing enzymes in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

Evaluation of uncertainty in input parameters to pharmacokinetic models and the resulting uncertainty in output

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

Variability of safe dose estimates when using complicated models of the carcinogenic process. A case study: methylene chloride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

Benzene disposition in the rat after exposure by inhalation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

Effect of dose on the absorption and excretion of [14C]benzene administered orally or by inhalation in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1992.TB00667.X

10.1111/J.1539-6924.1992.TB00667.X

21 January 2018

Identifiers

DOI

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19 December 2017

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19 December 2017