Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q46052989)
Watch
English
Enzymology of the polyenes pimaricin and candicidin biosynthesis.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
title
Enzymology of the polyenes pimaricin and candicidin biosynthesis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
main subject
natamycin
1 reference
based on heuristic
inferred from title
author
Jesús F Aparicio
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
author name string
Juan F Martín
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
language of work or name
English
0 references
publication date
1 January 2009
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
published in
Methods in Enzymology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
volume
459
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
page(s)
215-242
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
cites work
Identification of PimR as a positive regulator of pimaricin biosynthesis in Streptomyces natalensis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyene antibiotic biosynthesis gene clusters.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microbial cholesterol oxidases: bioconversion enzymes or signal proteins?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphate control of pabS gene transcription during candicidin biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Folate synthesis in plants: the last step of the p-aminobenzoate branch is catalyzed by a plastidial aminodeoxychorismate lyase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential roles of two SARP-encoding regulatory genes during tylosin biosynthesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction and secondary metabolism: prospects for controlling productivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for pabAB, a p-aminobenzoate synthase gene of Streptomyces venezuelae ISP5230, in chloramphenicol biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biosynthesis of deoxyamphotericins and deoxyamphoteronolides by engineered strains of Streptomyces nodosus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The candicidin gene cluster from Streptomyces griseus IMRU 3570.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p-Aminobenzoic acid and chloramphenicol biosynthesis in Streptomyces venezuelae: gene sets for a key enzyme, 4-amino-4-deoxychorismate synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Organizational and mutational analysis of a complete FR-008/candicidin gene cluster encoding a structurally related polyene complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pab gene of Streptomyces griseus, encoding p-aminobenzoic acid synthase, is located between genes possibly involved in candicidin biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure, function, and evolution of bacterial ATP-binding cassette systems
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An efficient gene transfer system for the pimaricin producer Streptomyces natalensis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and expression of a p-aminobenzoic acid synthetase gene of the candicidin-producing Streptomyces griseus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of the macrolide antibiotic pimaricin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutants blocked in streptomycin production in Streptomyces griseus - the role of A-factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoregulatory factors and communication in actinomycetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repeated polyketide synthase modules involved in the biosynthesis of a heptaene macrolide by Streptomyces sp. FR-008.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3-Amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and in vivo functional analysis by disruption of a gene encoding the gamma-butyrolactone autoregulator receptor from Streptomyces natalensis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of a BarX homologue (SngA) as a pleiotropic regulator in Streptomyces natalensis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphate control sequences involved in transcriptional regulation of antibiotic biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stereospecific acyl transfers on the erythromycin-producing polyketide synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific inhibition of candicidin biosynthesis by the lipogenic inhibitor cerulenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biosynthesis of polyene macrolide antibiotics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of a Gene Involved in Antibiotic Synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphate control of the biosynthesis of antibiotics and other secondary metabolites is mediated by the PhoR-PhoP system: an unfinished story
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Secretion systems for secondary metabolites: how producer cells send out messages of intercellular communication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complete nucleotide sequence and characterization of pSNA1 from pimaricin-producing Streptomyces natalensis that replicates by a rolling circle mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engineered biosynthesis of novel polyenes: a pimaricin derivative produced by targeted gene disruption in Streptomyces natalensis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the polyene macrolide P450 epoxidase from Streptomyces natalensis that converts de-epoxypimaricin into pimaricin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cholesterol Oxidases Act as Signaling Proteins for the Biosynthesis of the Polyene Macrolide Pimaricin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the mycosamine biosynthesis and attachment genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI factor, a novel type quorum-sensing inducer elicits pimaricin production in Streptomyces natalensis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycerol, ethylene glycol and propanediol elicit pimaricin biosynthesis in the PI-factor-defective strain Streptomyces natalensis npi287 and increase polyene production in several wild-type actinomycetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide transcriptomic and proteomic analysis of the primary response to phosphate limitation inStreptomyces coelicolor M145 and in a ΔphoP mutant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redesign of the coenzyme specificity of a dehydrogenase by protein engineering
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Starter unit choice determines the production of two tetraene macrolides, rimocidin and CE-108, in Streptomyces diastaticus var. 108.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The thioesterase domain from the pimaricin and erythromycin biosynthetic pathways can catalyze hydrolysis of simple thioester substrates.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The two-component PhoR-PhoP system controls both primary metabolism and secondary metabolite biosynthesis in Streptomyces lividans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of PhoP to promoters of phosphate-regulated genes in Streptomyces coelicolor: identification of PHO boxes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Target genes and structure of the direct repeats in the DNA-binding sequences of the response regulator PhoP in Streptomyces coelicolor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of inducing factors for virginiamycin production in Streptomyces virginiae.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Incomplete beta-ketone processing as a mechanism for polyene structural variation in the FR-008/candicidin complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904610-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0076-6879(09)04610-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PubMed publication ID
19362642
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19362642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362642%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit