(Q46062825)

19 December 2017

title

Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells (English)

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19 December 2017

estrogen-receptor negative breast cancer

main subject

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U Gundimeda

1

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19 December 2017

Z H Chen

series ordinal

2

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19 December 2017

R Gopalakrishna

series ordinal

3

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19 December 2017

language of work or name

English

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publication date

1 June 1996

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19 December 2017

Journal of Biological Chemistry

number of pages

11

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based on heuristic

inferred from page(s)

published in

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19 December 2017

volume

271

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19 December 2017

issue

23

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19 December 2017

page(s)

13504-13514

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19 December 2017

The pharmacology and clinical uses of tamoxifen

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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Protein kinase C and tumor promoters

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Multiple mechanisms of protein kinase C inhibition by triphenylacrylonitrile antiestrogens

21 January 2018

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Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells

21 January 2018

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Metabolism of tamoxifen by isolated rat hepatocytes. Identification of 1-[4-(2-hydroxyethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenyl-1-butene and the dependence of N-oxidation on oxygen availability

21 January 2018

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Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells

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Inhibition of cellular transformation by triphenylmethane: a novel chemopreventive agent

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Selective redistribution of protein kinase C isozymes by thapsigargin and staurosporine

21 January 2018

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Synthetic estrogens and tamoxifen as promoters of hepatocarcinogenesis.

21 January 2018

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The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat.

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Tamoxifen and the induction of cancer.

21 January 2018

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Rapid filtration assays for protein kinase C activity and phorbol ester binding using multiwell plates with fitted filtration discs

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The polyphosphoinositide phosphodiesterase of erythrocyte membranes

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New colorimetric cytotoxicity assay for anticancer-drug screening

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The metabolism of 17 beta-estradiol by lactoperoxidase: a possible source of oxidative stress in breast cancer

21 January 2018

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Enhanced interfacial catalysis and hydrolytic specificity of phospholipase A2 toward peroxidized phosphatidylcholine vesicles

21 January 2018

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Tamoxifen stimulates phospholipase D activity by an estrogen receptor-independent mechanism

21 January 2018

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Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA.

21 January 2018

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Nonphorbol tumor promoters okadaic acid and calyculin-A induce membrane translocation of protein kinase C.

21 January 2018

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A proposed mechanism of benzene toxicity: formation of reactive intermediates from polyphenol metabolites.

21 January 2018

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Semiquinone anion radicals of catechol(amine)s, catechol estrogens, and their metal ion complexes

21 January 2018

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Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound

21 January 2018

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21 January 2018

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Role of oxygen radicals in tumor promotion

21 January 2018

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Effects of chloroquine on lysosomal enzymes, NADPH-induced lipid peroxidation, and antioxidant enzymes of rat retina

21 January 2018

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Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture

21 January 2018

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Hydrogen peroxide formation and DNA base modification by tumor promoter-activated polymorphonuclear leukocytes

21 January 2018

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Peroxidase activation of tamoxifen and toremifene resulting in DNA damage and covalently bound protein adducts

21 January 2018

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Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin

21 January 2018

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Suppression of mouse mammary tumorigenesis by long-term tamoxifen therapy

21 January 2018

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Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen

21 January 2018

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Antiestrogen-binding sites distinct from the estrogen receptor: subecellular localization, ligand specificity, and distribution in tissues of the rat

21 January 2018

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Tamoxifen is a calmodulin antagonist in the activation of cAMP phosphodiesterase

21 January 2018

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Comparison of protein kinase C functional assays to clarify mechanisms of inhibitor action

21 January 2018

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Role of specific interactions between protein kinase C and triphenylethylenes in inhibition of the enzyme

21 January 2018

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Phenoxyl radical-induced thiol-dependent generation of reactive oxygen species: implications for benzene toxicity

21 January 2018

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The antioxidant action of tamoxifen and its metabolites. Inhibition of lipid peroxidation

21 January 2018

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Reduction of the membrane fluidity of human breast cancer cells by tamoxifen and 17 beta-estradiol

21 January 2018

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Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin. Effects on lipid peroxidation, hydroxyl radical generation and bleomycin-dependent damage to DNA

21 January 2018

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Stimulation of human polymorphonuclear leukocyte superoxide anion radical production by tumor promoters

21 January 2018

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An evaluation of peroxidase as a marker for estrogen action in normal mammary glands of mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.23.13504

1 reference

19 December 2017

1 reference

19 December 2017