(Q46067297)

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γ-Secretase inhibitor I induces apoptosis in chronic lymphocytic leukemia cells by proteasome inhibition, endoplasmic reticulum stress increase and notch down-regulation.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23001755%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

γ-Secretase inhibitor I induces apoptosis in chronic lymphocytic leukemia cells by proteasome inhibition, endoplasmic reticulum stress increase and notch down-regulation (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23001755%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

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endoplasmic reticulum

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1 reference

based on heuristic

inferred from title

chronic lymphocytic leukemia

1 reference

based on heuristic

inferred from title

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23001755%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Emanuela Rosati

1

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Europe PubMed Central

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8 March 2020

Filomena De Falco

3

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8 March 2020

Beatrice Del Papa

4

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8 March 2020

Katia Fettucciari

8

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8 March 2020

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Rita Sabatini

2

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8 March 2020

Franca Falzetti

5

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8 March 2020

Mauro Di Ianni

6

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8 March 2020

Laura Cavalli

7

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8 March 2020

Isabella Screpanti

10

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8 March 2020

Pierfrancesco Marconi

11

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8 March 2020

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17 October 2012

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8 March 2020

International Journal of Cancer

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8 March 2020

132

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8 March 2020

8

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8 March 2020

1940-1953

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8 March 2020

Chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1002%2FIJC.27863

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In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.

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Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells

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The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibition.

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Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

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21 January 2018

Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress.

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21 January 2018

Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL.

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Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

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Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.

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21 January 2018

ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

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A new genetic lesion in B-CLL: a NOTCH1 PEST domain mutation.

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

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Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

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Mechanisms of proteasome inhibitor action and resistance in cancer

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Roles of CHOP/GADD153 in endoplasmic reticulum stress

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Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

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Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

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The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

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