(Q46079015)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors (English)

1 reference

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24 January 2020

1 reference

15

1 reference

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24 January 2020

Jonathan C Welti

4

1 reference

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24 January 2020

Stephen Douglas Robinson

6

1 reference

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24 January 2020

Vassiliki Kostourou

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Kairbaan Hodivala-Dilke

17

1 reference

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24 January 2020

author name string

Andrew R Reynolds

1

1 reference

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24 January 2020

Ian R Hart

2

1 reference

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24 January 2020

Alan R Watson

3

1 reference

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24 January 2020

Rita G Silva

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Georges Da Violante

7

1 reference

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24 January 2020

Morgane Gourlaouen

8

1 reference

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24 January 2020

Mishal Salih

9

1 reference

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24 January 2020

Matt C Jones

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Dylan T Jones

11

1 reference

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24 January 2020

Garry Saunders

12

1 reference

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24 January 2020

Françoise Perron-Sierra

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Gordon C Tucker

16

1 reference

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24 January 2020

language of work or name

English

0 references

publication date

22 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

page(s)

392-400

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305413%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.1941

24 January 2020

exact match

0 references

cites work

Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.

1 reference

12 December 2020

Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

12 December 2020

Human malignant glioma therapy using anti-alpha(v)beta3 integrin agents.

1 reference

12 December 2020

A reevaluation of integrins as regulators of angiogenesis

1 reference

12 December 2020

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

1 reference

12 December 2020

Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

1 reference

12 December 2020

Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells

1 reference

12 December 2020

Integrins: molecular targets in cancer therapy

1 reference

12 December 2020

Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration

1 reference

12 December 2020

Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells.

1 reference

12 December 2020

Substituted benzocyloheptenes as potent and selective alpha(v) integrin antagonists

1 reference

12 December 2020

Integrin inhibitors reaching the clinic

1 reference

12 December 2020

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1 reference

12 December 2020

1 reference

12 December 2020

Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis

1 reference

12 December 2020

Integrin signaling is critical for pathological angiogenesis

1 reference

12 December 2020

alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin.

1 reference

12 December 2020

Moving membrane up to the front of migrating cells

1 reference

12 December 2020

VEGF-targeted therapy: mechanisms of anti-tumour activity.

1 reference

12 December 2020

Epidermal growth factor receptor distribution during chemotactic responses

1 reference

12 December 2020

Cancer biology and hormesis: human tumor cell lines commonly display hormetic (biphasic) dose responses

1 reference

12 December 2020

Assessment of the biological and pharmacological effects of the alpha nu beta3 and alpha nu beta5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors

1 reference

12 December 2020

Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors

1 reference

12 December 2020

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis

1 reference

12 December 2020

VEGF receptor signalling - in control of vascular function

1 reference

12 December 2020

Integrins in angiogenesis: multitalented molecules in a balancing act.

1 reference

12 December 2020

Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer

1 reference

12 December 2020

Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma.

1 reference

12 December 2020

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

1 reference

12 December 2020

Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography

1 reference

12 December 2020

Manganese-induced integrin affinity maturation promotes recruitment of alpha V beta 3 integrin to focal adhesions in endothelial cells: evidence for a role of phosphatidylinositol 3-kinase and Src

1 reference

12 December 2020

Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments

1 reference

12 December 2020

Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist

1 reference

12 December 2020

Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells

1 reference

12 December 2020

VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment

1 reference

12 December 2020

Endocytic transport of integrins during cell migration and invasion.

1 reference

12 December 2020

In vivo therapy of malignant melanoma by means of antagonists of alphav integrins

1 reference

12 December 2020

Alpha v integrin inhibitors and cancer therapy.

1 reference

12 December 2020

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists

1 reference

12 December 2020

A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer

1 reference

12 December 2020

In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts

1 reference

12 December 2020

PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading

1 reference

12 December 2020

alphavbeta3 integrin and angiogenesis: a moody integrin in a changing environment.

1 reference

12 December 2020

Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in beta3-integrin-deficient mice

1 reference

12 December 2020

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

1 reference

12 December 2020

Phase I and pharmacokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins αvβ3 and αvβ5 in patients with advanced solid tumours

1 reference

12 December 2020

Clinical translation of angiogenesis inhibitors

1 reference

12 December 2020

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

1 reference

12 December 2020

Vascular endothelial growth factor (VEGF) and its receptors

1 reference

12 December 2020

alphav beta 3 and alphav beta 5 integrin antagonists inhibit angiogenesis in vitro.

1 reference

12 December 2020

Inhibition of the alpha-nu integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo

1 reference

12 December 2020

Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

1 reference

12 December 2020

Superactivation of integrin alphavbeta3 by low antagonist concentrations

1 reference

12 December 2020