(Q46091349)

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Assessment of cryopreserved human hepatocytes as a model system to investigate sulfation and glucuronidation and to evaluate inhibitors of drug conjugation

scientific article published in May 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Assessment of cryopreserved human hepatocytes as a model system to investigate sulfation and glucuronidation and to evaluate inhibitors of drug conjugation (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

cryopreservation

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Michael Coughtrie

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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Z Riches

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

J Bloomer

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

A Patel

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

A Nolan

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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publication date

1 May 2009

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

39

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

374-381

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Interindividual variability in acetaminophen sulfation by human fetal liver: implications for pharmacogenetic investigations of drug-induced birth defects

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

The role of sulphate conjugation in the metabolism and disposition of oral and intravenous paracetamol in man.

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Differences in the single-oral-dose pharmacokinetics and urinary excretion of paracetamol and its conjugates between Hong Kong Chinese and Caucasian subjects

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Inter-subject and ethnic differences in paracetamol metabolism

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Cisapride raises the bioavailability of paracetamol by inhibiting its glucuronidation in man.

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Effect of nizatidine on paracetamol and its metabolites in human plasma

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Sulfinpyrazone C-glucuronidation is catalyzed selectively by human UDP-glucuronosyltransferase 1A9.

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Microscale culture of human liver cells for drug development.

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

UDP-glucuronosyltransferases and clinical drug-drug interactions

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Transport, Metabolism, and Hepatotoxicity of Flutamide, Drug–Drug Interaction with Acetaminophen Involving Phase I and Phase II Metabolites

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Human hepatocytes: isolation, cryopreservation and applications in drug development

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Differential inhibition of human liver and duodenum sulphotransferase activities by quercetin, a flavonoid present in vegetables, fruit and wine.

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Sulfotransferase (SULT) 1A1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Paracetamol interaction with oral contraceptive steroids: increased plasma concentrations of ethinyloestradiol

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Preclinical pharmacokinetics: an approach towards safer and efficacious drugs

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

The pivotal role of hepatocytes in drug discovery

1 reference

https://api.crossref.org/works/10.1080%2F00498250902763440

21 January 2018

Identifiers

10.1080/00498250902763440

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19280384%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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