(Q46093008)

19 December 2017

title

Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia (English)

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19 December 2017

author name string

Saunders Ching

series ordinal

1

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19 December 2017

Eric Vilain

series ordinal

2

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19 December 2017

publication date

1 September 2009

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19 December 2017

published in

Genesis

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19 December 2017

volume

47

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19 December 2017

issue

9

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19 December 2017

page(s)

628-637

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19 December 2017

The undifferentiated cell zone is a stem cell zone in adult rat adrenal cortex.

cites work

1 reference

A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans

21 January 2018

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Development of a steroidogenic factor 1/Cre transgenic mouse line

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HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

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Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function

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Haploinsufficiency of steroidogenic factor-1 in mice disrupts adrenal development leading to an impaired stress response.

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Pallister-Hall syndrome phenotype in mice mutant for Gli3

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A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

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The XtJ allele generates a Gli3 fusion transcript

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

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Melanocortin 2 receptor is required for adrenal gland development, steroidogenesis, and neonatal gluconeogenesis

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Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

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Fine tuning of adrenocortical functions by locally produced growth factors

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Sonic Hedgehog as a mediator of long-range signaling

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Morphologic features of the anencephalic adrenal gland in early pregnancy

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Wnt-4 deficiency alters mouse adrenal cortex function, reducing aldosterone production

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Sonic Hedgehog Stimulates Mouse Embryonic Stem Cell Proliferation by Cooperation of Ca2+/Protein Kinase C and Epidermal Growth Factor Receptor As Well as Gli1 Activation

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7 January 2021

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

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GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome

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A molecular pathway determining left-right asymmetry in chick embryogenesis

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A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.

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7 January 2021

A novel cell layer without corticosteroid-synthesizing enzymes in rat adrenal cortex: histochemical detection and possible physiological role

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Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism

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Mutations affecting segment number and polarity in Drosophila

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Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.

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Regulation of left-right asymmetries in the zebrafish by Shh and BMP4.

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Pbx1 is essential for adrenal development and urogenital differentiation

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Molecular cues for the development of adrenal chromaffin cells and their preganglionic innervation

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7 January 2021

GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization

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7 January 2021

Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1

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7 January 2021

Chronic stress induces adrenal hyperplasia and hypertrophy in a subregion-specific manner

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7 January 2021

Hedgehog: functions and mechanisms

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7 January 2021

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

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7 January 2021

A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

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Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis

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7 January 2021

Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin

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An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

1 reference

7 January 2021

Identifiers

DOI

10.1002/DVG.20532

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19 December 2017

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19 December 2017