(Q46096414)

19 December 2017

title

Structures and cytotoxic properties of trichoverroids and their macrolide analogues produced by saltwater culture of Myrothecium verrucaria (English)

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19 December 2017

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Albifimbria verrucaria

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(1R,3R,8R,24S,25S,26S,27R)-27-hydroxy-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,12,18,20-tetraene-26,2'-oxirane]-11,17,22-trione

Myrothecium verrucaria

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(1S,2S,3S,10S,11S,13R,15E,20R,23S,24S,25R,27R,29R)-1,23,29-trihydroxy-2,11,15,23-tetramethyl-4,12,18,26,30-pentaoxahexacyclo[22.3.1.13,27.110,13.02,20.020,25]triaconta-6,8,15-triene-5,17-dione

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13'-Acetyltrichoverrin B

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(1R,3R,8R,17R,24S,25S,26S,27R)-27-hydroxy-17-[(1R)-1-hydroxyethyl]-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,12,18,20-tetraene-26,2'-oxirane]-11,22-dione

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(1R,3R,8R,17R,24S,25S,26S,27R)-27-hydroxy-17-[(1S)-1-hydroxyethyl]-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,12,18,20-tetraene-26,2'-oxirane]-11,22-dione

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(1R,2S,3S,6Z,8E,10S,11S,13R,15E,20R,23S,24S,25R,27R,29R)-1,23,29-trihydroxy-2,11,15,23-tetramethyl-4,12,18,26,30-pentaoxahexacyclo[22.3.1.13,27.110,13.02,20.020,25]triaconta-6,8,15-triene-5,17-dione

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[(1S,2R,7R,11R,12S)-2-[[(E)-5-hydroxy-3-methylpent-2-enoyl]oxymethyl]-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl] (2Z,4E,6S,7R)-6,7-dihydroxyocta-2,4-dienoate

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(1R,3R,8R,12E,15R,17S,18S,25S,26S,27S,28R)-28-hydroxy-5,13,17,26-tetramethylspiro[2,10,16,24,29-pentaoxapentacyclo[23.2.1.115,18.03,8.08,26]nonacosa-4,12,19,21-tetraene-27,2'-oxirane]-11,23-dione

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(1R,3R,8R,12S,13R,17R,24R,25S,26S)-12-hydroxy-17-[(1S)-1-hydroxyethyl]-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,18,20-triene-26,2'-oxirane]-11,22-dione

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(1R,3R,8R,12S,13R,17R,24R,25S,26S)-12-hydroxy-17-[(1R)-1-hydroxyethyl]-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,18,20-triene-26,2'-oxirane]-11,22-dione

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[(1S,2R,7R,11R,12S)-2-[[(E)-5-hydroxy-3-methylpent-2-enoyl]oxymethyl]-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl] (6S,7R)-6,7-dihydroxyocta-2,4-dienoate

1 reference

(1R,3R,8R,12E,17S,18E,20Z,24S,25S,26S,27R)-27-hydroxy-17-[(1R)-1-hydroxyethyl]-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,12,18,20-tetraene-26,2'-oxirane]-11,22-dione

1 reference

1 reference

(1R,3R,8R,12S,13R,24R,25S,26S)-12-hydroxy-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,18,20-triene-26,2'-oxirane]-11,17,22-trione

1 reference

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[(1S,2R,7R,11R,12S)-2-[[(E)-5-hydroxy-3-methylpent-2-enoyl]oxymethyl]-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl] (6S,7S)-6,7-dihydroxyocta-2,4-dienoate

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Taro Amagata

1

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19 December 2017

Christopher Rath

2

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19 December 2017

Jérôme F Rigot

3

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19 December 2017

Nick Tarlov

4

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19 December 2017

Karen Tenney

5

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19 December 2017

Frederick A Valeriote

6

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19 December 2017

Phillip Crews

7

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19 December 2017

Journal of Medicinal Chemistry

language of work or name

English

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publication date

23 August 2003

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16 September 2022

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19 December 2017

volume

46

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19 December 2017

issue

20

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19 December 2017

page(s)

4342-4350

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19 December 2017

Roridin L, M and verrucarin M, new macrocyclic trichothecene group antitumor antibiotics, from Myrothecium verrucaria

cites work

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.54.980

Two new roridins isolated from Myrothecium sp

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.54.517

Identifiers

DOI

10.1021/JM030090T

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19 December 2017

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19 December 2017