(Q46099051)

English

The Pbx family of proteins is strongly upregulated by a post-transcriptional mechanism during retinoic acid-induced differentiation of P19 embryonal carcinoma cells.

scientific article published in April 1997

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scholarly article

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Europe PubMed Central

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3 November 2019

The Pbx family of proteins is strongly upregulated by a post-transcriptional mechanism during retinoic acid-induced differentiation of P19 embryonal carcinoma cells (English)

1 reference

Europe PubMed Central

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3 November 2019

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embryonal carcinoma

1 reference

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1

1 reference

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3 November 2019

author name string

M P Kamps

2

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3 November 2019

publication date

1 April 1997

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3 November 2019

Mechanisms of Development

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3 November 2019

63

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3 November 2019

1

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3 November 2019

5-14

1 reference

Europe PubMed Central

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3 November 2019

The translational repression mediated by the platelet-derived growth factor 2/c-sis mRNA leader is relieved during megakaryocytic differentiation

1 reference

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Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids

1 reference

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7 January 2021

based on heuristic

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The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

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Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

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The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a receptor for the morphogen retinoic acid

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The Max transcription factor network: involvement of Mad in differentiation and an approach to identification of target genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subse

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a retinoic acid responsive enhancer 3' of the murine homeobox gene Hox-1.6

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain--demonstration of Hox-dependent targeting of E2a-Pbx1 in viv

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear receptor that identifies a novel retinoic acid response pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear import of the homeodomain protein extradenticle in response to Wg and Dpp signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of four homeobox gene clusters in human embryonal carcinoma cells induced to differentiate by retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A human retinoic acid receptor which belongs to the family of nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a retinoic acid response element upstream of the murine Hox-4.2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Localization of Pbx1 transcripts in developing rat embryos

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

3,5,3'-Triiodo-L-thyronine induces cardiac myocyte differentiation but not neuronal differentiation in P19 teratocarcinoma cells in a dose dependent manner

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Morphogenesis of malformations in hamsters caused by retinoic acid: relation to dose and stage at treatment

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The optimal binding sequence of the Hox11 protein contains a predicted recognition core motif

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Local application of retinoic acid to the limb bond mimics the action of the polarizing region

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of HOX-2 genes in P19 embryocarcinoma cells is dependent on retinoic acid receptor alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2897%2900669-2

7 January 2021

based on heuristic

inferred from DOI database lookup

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