(Q46121053)

English

Activation of macrophage peroxisome proliferator-activated receptor-gamma by diclofenac results in the induction of cyclooxygenase-2 protein and the synthesis of anti-inflammatory cytokines

scientific article published on 15 February 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

Activation of macrophage peroxisome proliferator-activated receptor-gamma by diclofenac results in the induction of cyclooxygenase-2 protein and the synthesis of anti-inflammatory cytokines (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

4

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

author name string

Regina M Botting

2

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

Amrish N Joshi

3

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

Paul R Colville-Nash

5

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

publication date

15 February 2009

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

327

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

1-2

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

101-110

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

Cyclo-oxygenase and nitric oxide synthase isoforms in rat carrageenin-induced pleurisy

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0048-Y

21 January 2018

PPAR: a mediator of peroxisome proliferator action

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0048-Y

21 January 2018

Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor gamma and oxidized alkyl phospholipids from oxidized low density lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of prostaglandin synthesis up-regulates cyclooxygenase-2 induced by lipopolysaccharide and peroxisomal proliferators

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diclofenac antagonizes peroxisome proliferator-activated receptor-gamma signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: evidence for intron 1 retention

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol ester and epidermal growth factor enhance the expression of two inducible prostaglandin H synthase genes in rat tracheal epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of peroxisomal beta-oxidation by nonsteroidal anti-inflammatory drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the glycosylation sites in cyclooxygenase-2 using mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible cyclooxygenase-derived 15-deoxyΔ12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta and the immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Prostaglandin Synthetase in Brain explains the Anti-pyretic Activity of Paracetamol (4-Acetamidophenol)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diclofenac sodium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory effects of prostacyclin (PGI2) and 6-oxo-PGF1α in the rat paw

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of transforming growth factor beta1 and its receptors by the Kruppel-like factor Zf9/core promoter-binding protein and Sp1. Potential mechanisms for autocrine fibrogenesis in response to injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor gamma 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetaminophen-induced hypothermia in mice is mediated by a prostaglandin endoperoxide synthase 1 gene-derived protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretory leukocyte protease inhibitor suppresses the production of monocyte prostaglandin H synthase-2, prostaglandin E2, and matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-gamma: counter-regulatory activity by IFN-gamma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The involvement of a cyclooxygenase 1 gene-derived protein in the antinociceptive action of paracetamol in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparing celecoxib with traditional nonsteroidal anti-inflammatory drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

More pronounced inhibition of cyclooxygenase 2, increase in blood pressure, and reduction of heart rate by treatment with diclofenac compared with celecoxib and rofecoxib

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced infiltration and increased apoptosis of leukocytes at sites of inflammation by systemic administration of a membrane-permeable IkappaBalpha repressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of hepatic microsomal CYP4A activity and of peroxisomal beta-oxidation by two non-steroidal anti-inflammatory drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible cyclooxygenase may have anti-inflammatory properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/19219624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-009-0048-Y

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19219624

ResearchGate publication ID

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