(Q46121537)

19 December 2017

title

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists (English)

1 reference

19 December 2017

author name string

Lyons DS

1

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19 December 2017

Lieberman SA

2

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19 December 2017

Hampl J

3

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19 December 2017

Boniface JJ

4

1 reference

19 December 2017

Chien Y

5

1 reference

19 December 2017

Berg LJ

6

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19 December 2017

Davis MM

7

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19 December 2017

language of work or name

English

0 references

publication date

1 July 1996

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19 December 2017

published in

Immunity

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19 December 2017

volume

5

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19 December 2017

page(s)

53-61

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19 December 2017

issue

1

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19 December 2017

Crystal structure of the beta chain of a T cell antigen receptor

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Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

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Isolation and characterization of antigen-la complexes involved in T cell recognition

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity

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The fine specificity of antigen and la determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c

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T cell receptor antagonists and partial agonists

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Solid-phase binding of class I and II MHC proteins: immunoassay and T cell recognition

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Real-time competitive kinetic analysis of interactions between low-molecular-weight ligands in solution and surface-immobilized receptors.

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7 January 2021

Essential flexibility in the T-cell recognition of antigen

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Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation

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Expression of T Cell Antigen Receptor Heterodimers in a Lipid-Linked Form

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7 January 2021

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

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7 January 2021

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

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Kinetic proofreading in T-cell receptor signal transduction

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7 January 2021

Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists

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7 January 2021

Kinetic discrimination in T-cell activation

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The nature of major histocompatibility complex recognition by gamma delta T cells.

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7 January 2021

Antigen analogs/MHC complexes as specific T cell receptor antagonists

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7 January 2021

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

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Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

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7 January 2021

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

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High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins

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7 January 2021

A surface plasmon resonance assay for the binding of influenza virus hemagglutinin to its sialic acid receptor

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7 January 2021

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

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7 January 2021

Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59

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7 January 2021

Continuous proliferation of murine antigen-specific helper T lymphocytes in culture

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7 January 2021

Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH

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7 January 2021

Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activity

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7 January 2021

10.1016/S1074-7613(00)80309-X

Identifiers

DOI

1 reference

19 December 2017

PubMed ID

8758894

1 reference

19 December 2017