(Q46122845)

19 December 2017

title

Inhibition of proteasome activity blocks cell cycle progression at specific phase boundaries in African trypanosomes (English)

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19 December 2017

author name string

Mutomba MC

1

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19 December 2017

To WY

2

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19 December 2017

Hyun WC

3

1 reference

19 December 2017

Wang CC

4

1 reference

19 December 2017

publication date

1 December 1997

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19 December 2017

Molecular and Biochemical Parasitology

published in

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19 December 2017

volume

90

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19 December 2017

issue

2

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19 December 2017

page(s)

491-504

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19 December 2017

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

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7 January 2021

Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.

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7 January 2021

Proteolysis, proteasomes and antigen presentation

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7 January 2021

The ubiquitin system for protein degradation

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7 January 2021

Structure and functions of the 20S and 26S proteasomes

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The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

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In vivo assembly of the proteasomal complexes, implications for antigen processing

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7 January 2021

Purification and characterization of proteasomes from Trypanosoma brucei

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7 January 2021

Identification and characterization of an activated 20S proteasome in Trypanosoma brucei

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7 January 2021

Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells

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7 January 2021

A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line

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7 January 2021

The neuritogenesis inducer lactacystin arrests cell cycle at both G0/G1 and G2 phases in neuro 2a cells

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7 January 2021

Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells

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7 January 2021

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

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7 January 2021

Activation of the cell death program by inhibition of proteasome function

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7 January 2021

Proteasome activity is required for the stage-specific transformation of a protozoan parasite

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7 January 2021

Differentiation of a culture-adapted mutant bloodstream form of Trypanosoma brucei into the procyclic form results in growth arrest of the cells

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7 January 2021

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

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7 January 2021

Apoptosis (the 1992 Frank Rose Memorial Lecture).

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7 January 2021

Cyclin ubiquitination: the destructive end of mitosis

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7 January 2021

How proteolysis drives the cell cycle

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7 January 2021

An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae

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7 January 2021

An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells

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7 January 2021

Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae

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7 January 2021

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

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7 January 2021

Defective mitosis due to a mutation in the gene for a fission yeast 26S proteasesubunit

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7 January 2021

Isolation of a mitotic-like cyclin homologue from the protozoan Trypanosoma brucei

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7 January 2021

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7 January 2021

Regulated expression of cyclin-1 during differentiation of Trypanosoma brucei from bloodstream form to procyclic form

1 reference

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7 January 2021

10.1016/S0166-6851(97)00197-7

Identifiers

DOI

1 reference

19 December 2017

1 reference

19 December 2017