(Q46122867)

19 December 2017

title

Role of NF-kappaB signaling pathway in increased tumor necrosis factor-alpha-induced apoptosis of lymphocytes in aged humans (English)

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19 December 2017

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S Gupta

1

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19 December 2017

R Bi

2

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19 December 2017

C Kim

3

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19 December 2017

S Chiplunkar

4

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19 December 2017

L Yel

5

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19 December 2017

S Gollapudi

6

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19 December 2017

publication date

1 February 2005

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19 December 2017

Cell Death & Differentiation

published in

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19 December 2017

volume

12

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19 December 2017

issue

2

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19 December 2017

page(s)

177-183

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19 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401557

exact match

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Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses

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Induction of apoptosis in mature T cells by tumour necrosis factor

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Transducing signals of life and death

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Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

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Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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NF-kappaB regulation in the immune system

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Missing pieces in the NF-kappaB puzzle

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NF-kappaB at the crossroads of life and death

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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Antiapoptotic function of NF-kappaB in T lymphocytes is influenced by their differentiation status: roles of Fas, c-FLIP, and Bcl-xL.

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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Increased cytokine production in mononuclear cells of healthy elderly people

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Tumor necrosis factor-alpha-induced apoptosis in T cells from aged humans: a role of TNFR-I and downstream signaling molecules

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7 January 2021

Effect of age on molecular signaling of TNF-α-induced apoptosis in human lymphocytes

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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

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Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

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Immunodeficiency of the elderly.

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7 January 2021

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Early steps in T cell development are affected by aging

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Membrane signal transduction in T cells in aging humans

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Apoptosis and ageing.

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7 January 2021

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Increased activity of caspase 3 and caspase 8 in anti-Fas-induced apoptosis in lymphocytes from ageing humans

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7 January 2021

Molecular and biochemical pathways of apoptosis in lymphocytes from aged humans

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7 January 2021

Molecular steps of cell suicide: an insight into immune senescence

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7 January 2021

Excessive apoptosis of mature T lymphocytes is a characteristic feature of human immune senescence

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7 January 2021

Susceptibility to apoptosis of T lymphocytes from elderly humans is associated with increased in vivo expression of functional Fas receptors

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7 January 2021

A role of fas-associated death domain (FADD) in increased apoptosis in aged humans

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7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

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7 January 2021

Nuclear factor-kappaB induction in CD45RO+ and CD45RA+ T cell subsets during aging.

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7 January 2021

Diminished responsiveness of senescent normal human fibroblasts to TNF-dependent proliferation and interleukin production is not due to its effect on the receptors or on the activation of a nuclear factor NF-kappa B.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401557

7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401557

7 January 2021

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

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7 January 2021

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401557

7 January 2021

Endogenous inhibitors of caspases

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7 January 2021

A role of inhibitor of apoptosis (IAP) proteins in increased lymphocyte apoptosis in aged humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401557

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401557

1 reference

19 December 2017

PubMed ID

15647756

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19 December 2017