(Q46123166)

English

Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment

scientific article published on 13 February 2009

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Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

inflammatory bowel diseases

1 reference

based on heuristic

inferred from title

author name string

Kan Uchiyama

1

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

Makoto Nakamura

2

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

Takahiro Kubota

3

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

Tateki Yamane

4

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

Kiyotaka Fujise

5

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

Hisao Tajiri

6

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

publication date

13 February 2009

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

Journal of Gastroenterology

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

44

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

3

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

197-203

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

Explaining TPMT genotype/phenotype discrepancy by haplotyping of TPMT*3A and identification of a novel sequence variant, TPMT*23.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-throughput detection of multiple genetic polymorphisms influencing drug metabolism with mismatch primers in allele-specific polymerase chain reaction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allelotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azathioprine in Rheumatoid Arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of thiopurine methyltransferase polymorphism in a Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequency distribution of thiopurine S-methyltransferase activity in red blood cells of a healthy Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TPMT in the treatment of Crohn's disease with azathioprine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequencies of thiopurine S-methyltransferase mutant alleles (TPMT*2, *3A, *3B and *3C) in 151 healthy Japanese subjects and the inheritance of TPMT*3C in the family of a propositus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azathioprine for Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical evaluation of a new antimetabolite, 6-mercaptopurine, in the treatment of leukemia and allied diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-dependent influence of 5-aminosalicylates on thiopurine metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Symposium on immunosuppressive drugs. Biochemistry and pharmacology of purine analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiopurine methyltransferase activity in American white subjects and black subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

6-Mercaptopurine: effects in mouse sarcoma 180 and in normal animals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ITPA genotyping is not predictive for the development of side effects in AZA treated inflammatory bowel disease patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiopurine methyltransferase activity in the Jewish population of Israel

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency in the Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of collagen diseases with cytostatics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19214663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00535-008-2307-1

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19214663

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