(Q46131414)

19 December 2017

title

Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation (English)

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19 December 2017

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Fanton CP

1

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19 December 2017

McMahon M

series ordinal

2

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19 December 2017

Pieper RO

series ordinal

3

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19 December 2017

language of work or name

English

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publication date

15 March 2001

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19 December 2017

Journal of Biological Chemistry

published in

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19 December 2017

volume

276

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19 December 2017

issue

22

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19 December 2017

page(s)

18871-18877

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19 December 2017

https://api.crossref.org/works/10.1074%2FJBC.M011514200

1 reference

Increasing complexity of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Signal transduction from multiple Ras effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Interaction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

A molecular genetic model of astrocytoma histopathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Analysis of Epidermal Growth Factor Receptor Gene Amplification and Alteration in Stereotactic Biopsies of Brain Tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Proliferation of human malignant astrocytomas is dependent on Ras activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Senescence of human fibroblasts induced by oncogenic Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Activated Raf-1 causes growth arrest in human small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Restoration of growth arrest by p16INK4, p21WAF1, pRB, and p53 is dependent on the integrity of the endogenous cell-cycle control pathways in human glioblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Induction of senescence in human malignant glioma cells by p16INK4A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small-cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

A role for E2F1 in Ras activation of p21(WAF1/CIP1) transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Dormant tumor-suppressor pathways in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011514200

21 January 2018

Identifiers

DOI

10.1074/JBC.M011514200

1 reference

19 December 2017

1 reference

19 December 2017