(Q46153957)

English

The stem cell factor-c-KIT pathway must be inhibited to enable apoptosis induced by BCR-ABL inhibitors in chronic myelogenous leukemia cells

scientific article published on 22 January 2009

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scholarly article

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

The stem cell factor-c-KIT pathway must be inhibited to enable apoptosis induced by BCR-ABL inhibitors in chronic myelogenous leukemia cells (English)

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

1 reference

based on heuristic

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author name string

F Belloc

1

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

K Airiau

2

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

M Jeanneteau

3

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

M Garcia

4

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

E Guérin

5

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

E Lippert

6

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

F Moreau-Gaudry

7

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

F-X Mahon

8

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

publication date

22 January 2009

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

23

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

4

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

679-685

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

https://scigraph.springernature.com/pub.10.1038/leu.2008.364

0 references

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

STAT5-Dependent CyclinD1 and Bcl-xL expression in Bcr-Abl-transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Cytokine-mediated cell survival

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

A sequential blockade strategy for the design of combination therapies to overcome oncogene addiction in chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Erlotinib as a single agent in select subsets of patients with advanced non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

High incidence of BCR-ABL kinase domain mutations and absence of mutations of the PDGFR and KIT activation loops in CML patients with secondary resistance to imatinib

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

21 January 2018

Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

7 January 2021

based on heuristic

inferred from DOI database lookup

Imatinib and nilotinib induce apoptosis of chronic myeloid leukemia cells through a Bim-dependant pathway modulated by cytokines

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcr-abl translocation can occur during the induction of multidrug resistance and confers apoptosis resistance on myeloid leukemic cell lines

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcr-Abl resistance screening predicts a limited spectrum of point mutations to be associated with clinical resistance to the Abl kinase inhibitor nilotinib (AMN107)

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.364

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/LEU.2008.364

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19158834

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