(Q46155945)

20 December 2017

title

Inhibition of HDAC3 as a strategy for developing novel diabetes therapeutics (English)

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20 December 2017

author name string

Bennett C Meier

series ordinal

1

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20 December 2017

Bridget K Wagner

series ordinal

2

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20 December 2017

publication date

1 April 2014

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20 December 2017

published in

Epigenomics

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20 December 2017

volume

6

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20 December 2017

issue

2

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20 December 2017

page(s)

209-214

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20 December 2017

Cancer biology: mechanism of antitumour action of vorinostat (suberoylanilide hydroxamic acid), a novel histone deacetylase inhibitor

cites work

1 reference

Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia

21 January 2018

1 reference

Role of NF-kappaB in beta-cell death

21 January 2018

1 reference

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

21 January 2018

1 reference

Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

21 January 2018

1 reference

Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

21 January 2018

1 reference

Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis

21 January 2018

1 reference

The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro

21 January 2018

1 reference

Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function

21 January 2018

1 reference

Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.

21 January 2018

1 reference

Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression

21 January 2018

1 reference

Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells

21 January 2018

1 reference

The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice

21 January 2018

1 reference

Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice.

21 January 2018

1 reference

Checkpoints in the progression of autoimmune disease: lessons from diabetes models

21 January 2018

1 reference

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice

21 January 2018

1 reference

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

21 January 2018

1 reference

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation.

21 January 2018

1 reference

Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors

21 January 2018

1 reference

Epigenetic regulation of inflammation: progressing from broad acting histone deacetylase (HDAC) inhibitors to targeting specific HDACs.

21 January 2018

1 reference

Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue

21 January 2018

1 reference

HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding

21 January 2018

1 reference

Histone deacetylase 9 is a negative regulator of adipogenic differentiation

21 January 2018

1 reference

AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.

21 January 2018

1 reference

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis

21 January 2018

1 reference

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

21 January 2018

1 reference

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

21 January 2018

1 reference

Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.

21 January 2018

1 reference

The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes

21 January 2018

1 reference

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

21 January 2018

1 reference

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo

21 January 2018

1 reference

Does an emergency visit to the ER make microRNAs stronger during stress?

21 January 2018

1 reference

Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly.

21 January 2018

1 reference

HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner

21 January 2018

1 reference

Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma

21 January 2018

1 reference

Modulation of splicing events in histone deacetylase 3 by various extracellular and signal transduction pathways.

21 January 2018

1 reference

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/EPI.14.11

1 reference

20 December 2017

release_bkdfbsbxwjaudkq4kdnv3atgae

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/bkdfbsbxwjaudkq4kdnv3atgae

mapped directly with Wikidata item

24 November 2022

based on heuristic

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20 December 2017