(Q46164878)

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Functional role of fumarate site Glu59 involved in allosteric regulation and subunit-subunit interaction of human mitochondrial NAD(P)+-dependent malic enzyme.

scientific article published on 12 January 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19141113%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Functional role of fumarate site Glu59 involved in allosteric regulation and subunit-subunit interaction of human mitochondrial NAD(P)+-dependent malic enzyme (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19141113%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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19 January 2020

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Ju-Yi Hsieh

1

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19 January 2020

Yu-Hsiu Chiang

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19141113%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Kuan-Yu Chang

3

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19 January 2020

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12 January 2009

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19 January 2020

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19 January 2020

276

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19 January 2020

4

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19 January 2020

983-994

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19 January 2020

A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme

1 reference

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21 January 2018

Structure of a closed form of human malic enzyme and implications for catalytic mechanism

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Crystal structure of the malic enzyme from Ascaris suum complexed with nicotinamide adenine dinucleotide at 2.3 A resolution

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Structure and function of malic enzymes, a new class of oxidative decarboxylases

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Purification, cDNA cloning and heterologous expression of the human mitochondrial NADP(+)-dependent malic enzyme

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Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362

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21 January 2018

Deviant energetic metabolism of glycolytic cancer cells

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21 January 2018

Malic enzyme and glucose 6-phosphate dehydrogenase gene expression increases in rat liver cirrhogenesis.

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21 January 2018

Glycolysis, glutaminolysis and cell proliferation

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21 January 2018

An NAD- and NADP-dependent malic enzyme with regulatory properties in rat liver and adrenal cortex mitochondrial fractions.

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21 January 2018

Characterization of the functional role of allosteric site residue Asp102 in the regulatory mechanism of human mitochondrial NAD(P)+-dependent malate dehydrogenase (malic enzyme).

1 reference

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21 January 2018

Mechanism of activation of the NAD-malic enzyme from Ascaris suum by fumarate

1 reference

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21 January 2018

Ascaris suum NAD-malic enzyme is activated by L-malate and fumarate binding to separate allosteric sites

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21 January 2018

Dual functional roles of ATP in the human mitochondrial malic enzyme

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21 January 2018

Functional roles of ATP-binding residues in the catalytic site of human mitochondrial NAD(P)+-dependent malic enzyme

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21 January 2018

Crystallographic studies on Ascaris suum NAD-malic enzyme bound to reduced cofactor and identification of an effector site

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21 January 2018

Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate

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21 January 2018

Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism

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21 January 2018

Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues

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21 January 2018

Structural basis of the allosteric behaviour of phosphofructokinase

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Fructose 2,6-bisphosphate 2 years after its discovery

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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21 January 2018

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

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21 January 2018

Modern analytical ultracentrifugation in protein science: a tutorial review

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On the analysis of protein self-association by sedimentation velocity analytical ultracentrifugation

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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21 January 2018

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